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The safest recreational drug becomes even safer

Mindset Pharma Announces Additional Preclinical Results Suggesting Superior Efficacy and Improved Safety in Head-to-Head Comparison to Psilocybin for its First Lead Clinical Candidate, MSP-1014

Magic mushrooms are the safest recreational drug according to a recent study, but Mindset Pharma (MSET) is working to make them even safer.

The company found that its patent-pending psychedelic compound, MSP-1014, may be more effective, safer, and more scalable than psilocybin. Researchers discovered that MSP-1014 more than doubled the head twitch responses in mice, an indicator of serotonin 5-HT2A receptor activity, which is tied to psychedelic experiences. MSP-1014 did not cause body temperature to drop, which was seen with psilocybin.

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Compass Pathways conducts world’s largest psilocybin therapy trial

COMPASS Pathways completes COMP360 psilocybin therapy administration for 216 patients in large-scale phase IIb psilocybin therapy trial for treatment-resistant depression

Move over Prozac, Compass Pathways (CMPS) just made major progress in psychedelic treatment for depression. The company is conducting the world’s largest psilocybin therapy trial for its proprietary psychedelic compound, COMP360, which targets treatment-resistant depression. So far, 216 patients have had psilocybin therapy sessions at Compass’s 22 trial sites across 10 countries, with 14 more patients completing sessions over the next two weeks. Researchers will follow-up with each patient 12 weeks after the sessions and will publish the findings by the end of this year. Other studies have found that psilocybin is 4 times more effective than typical antidepressants – let’s see what Compass’s new research reveals.

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MYND Life Sciences makes progress in treating Alzheimer’s and dementia with psilocybin

MYND Life Sciences Expands Intellectual Portfolio to Target Alzheimer’s disease and related forms of Dementia with Chemical Subclasses of Psilocybin Analogues

You won’t want to forget about this company when choosing your investments. The research team at MYND Life Sciences Inc. (MYND) has been exploring new subclasses of psilocybin that have shown potential to delay or reverse Alzheimer’s disease and other forms of dementia. The preclinical research has shown significant progress, and MYND aims to commence clinical trials to advance the research.

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