Posted on

Avoid daily antidepressants with a monthly trip

Single Dose of Psychedelic Compound Psilocybin Can Remodel Connections in the Brain

It’s clear that psychedelics are helpful in treating depression, but have you ever wondered why they work so well?

When someone suffers from depression or chronic stress, they typically have a reduction in neural connections, but psychedelics might be able to reverse this. A study at Yale just revealed that one dose of psilocybin can increase these neuronal connections by 10%. The dose also increased the density of dendritic spines (those little spikey things on nerve cells), making the connections stronger. About a third of the new connections remained intact after 34 days.

PDF of article

PDF of study

Posted on

One dose of psilocybin eases migraines in recent study

A single dose of psilocybin has a lasting therapeutic effect on migraine headache, according to a new placebo-controlled study

A double-blind, placebo-controlled study found that a single low dosage of psilocybin effectively reduced the severity of migraine pain and functional impairments in participants with frequent migraines. Participants reported that the therapeutic effect lasted for at least two weeks with no adverse side effects, supporting years of anecdotal reports that psilocybin eases migraine symptoms.

PDF of article

Posted on

Johns Hopkins study found that psilocybin is more effective at treating nicotine addiction than the leading drug, with 80% quitting after single dose

More Than A Trip: Psychedelic Drugs Being Used To Help People Quit Smoking In Just One Dose

A study at Johns Hopkins Behavioral Biology Research Center found that 80% of participants were able to quit smoking for at least six months after taking one dose of psilocybin, including one participant who was a heavy smoker for over 25 years. This suggests that psilocybin therapy is over twice as effective as the leading smoking cessation drug, varenicline, which has a 35% success rate after six months. Dr. Albert Garcia-Romeu explains that psilocybin is effective for treating addiction because it changes the way the brain makes connections, which can “interrupt old patterns, well-worn neuro pathways, or habits.”

PDF of article

PDF of study