Awakn Life Sciences Inc. and 1169082 B.C. Ltd. Enter into Binding Agreement for Reverse Takeover Transaction

Vancouver, British Columbia–(Newsfile Corp. – May 17, 2021) – 1169082 B.C. Ltd. (the “Company“) is pleased to announce that it has entered into a definitive binding amalgamation agreement dated May 13, 2021 (the “Amalgamation Agreement“) among the Company, 2835517 Ontario Ltd. (“Subco“), a wholly-owned subsidiary of the Company, and Awakn Life Sciences Inc. (“Awakn“), which, subject to certain conditions and applicable shareholder and regulatory approvals, will result in a reverse takeover of the Company by Awakn (the “Proposed Transaction“). The resulting issuer from the Proposed Transaction (the “Resulting Issuer“) will carry on the business of Awakn.

The Proposed Transaction

Pursuant to the terms of the Amalgamation Agreement, the Proposed Transaction will be completed by way of a three-cornered amalgamation involving Subco amalgamating with Awakn to form a single, wholly-owned subsidiary of the Resulting Issuer. Shareholders of Awakn shall receive one (1) post-Consolidation (as defined below) common share of the Resulting Issuer for each common share of Awakn, and convertible securities of Awakn shall be exchanged for convertible securities of the Resulting Issuer on substantially the same terms and exercisable into such number of Resulting Issuer shares as the holder of such Awakn convertible security would have been entitled to, if it had been exercised prior to the completion of the Proposed Transaction.

In connection with the Proposed Transaction, the Company will reconstitute its board of directors and management team, consolidate all of its issued and outstanding shares on the basis of 1 post-consolidation share for every 42.5105 pre-consolidation shares (the “Consolidation“), and change its name to “Awakn Life Sciences Corp.” or such other name as may be accepted by the relevant regulatory authorities (the “Name Change“) and the Resulting Issuer will conduct its business under the new name. As a condition to the Proposed Transaction, the common shares of the Resulting Issuer will have been conditionally approved for listing on the NEO Exchange Inc. (“NEO“), and the listing of the Resulting Issuer shares on NEO will be subject to the satisfaction of all conditions of listing required by NEO.

The Amalgamation Agreement provides for certain other conditions to the completion of the Proposed Transaction, including Awakn completing a brokered financing (the “Concurrent Financing“), the Company obtaining the necessary shareholder and board approvals to reconstitute its board and management, and effect the Consolidation and the Name Change, Awakn obtaining the necessary shareholder and board approvals to effect the Proposed Transaction, and other closing conditions customary for transactions of the nature of the Proposed Transaction.

Concurrent Financing

In connection with the Proposed Transaction, Awakn plans to complete a private placement of subscription receipts with a syndicate of agents (the “Agents“) co-led by Canaccord Genuity Corp. and Eight Capital (together, the “Co-Lead Agents“) to raise up to 3,200,000 subscription receipts on a commercially reasonable efforts basis (“Subscription Receipts“) at a price of $2.50 per Subscription Receipt (the “Issue Price“) for gross proceeds of up to $8,000,000. In addition, the Agents shall have the option, exercisable at any time prior to the closing date of the Concurrent Financing, to increase the size of the financing by up to 480,000 additional Subscription Receipts for additional gross proceeds of up to $1,200,000. Up to $1,000,000 of the Concurrent Financing may be subscribed for by “President’s List” investors.

The gross proceeds of the Concurrent Financing, less 50% of the Agents’ cash commission (as described below) and certain expenses of the Agents, will be deposited in escrow on the closing date of the Concurrent Financing until the satisfaction of certain release conditions, including that all conditions precedent to the Proposed Transaction have been met (the “Release Conditions“).

Upon the satisfaction of the Release Conditions, each Subscription Receipt will be converted into one common share in the capital of Awakn (each, an “Awakn Share“) without payment of any additional consideration or further action on the part of the holder thereof. At the effective time of the Proposed Transaction, each Awakn Share will be exchanged for one Resulting Issuer Share (on a post-consolidation basis).

In the event that the Release Conditions have not been satisfied prior to 120 days following the closing of the Concurrent Financing (the “Escrow Release Deadline“), or Awakn advises the Co-Lead Agents or announces to the public that it does not intend to satisfy the Release Conditions or that the Proposed Transaction has been terminated, the aggregate Issue Price of the Subscription Receipts (plus any interest earned thereon) shall be returned to the applicable holders of the Subscription Receipts (net of any applicable withholding taxes), and such Subscription Receipts shall be automatically cancelled and be of no further force and effect.

In consideration for their services in connection with the Concurrent Financing, the Agents will be entitled to receive (i) a cash commission (the “Agents’ Commission“) equal to 7.0% of the gross proceeds raised under the offering (provided that the Agents’ Commission for President’s List subscribers will be 3.5%); and (ii) that number of warrants (the “Agents’ Warrants“) as is equal to 7.0% of the aggregate number of Subscription Receipts issued under the offering (provided that the Agents shall receive that number of Agents’ Warrants as is equal to 3.5% for President’s List subscribers). Each Agents’ Warrant will be exercisable into one Awakn Share at the Issue Price for a period of 24 months from the closing date of the Proposed Transaction. In connection with the completion of the Proposed Transaction, each Agents’ Warrant will be exchanged into one compensation warrant of the Resulting Issuer, which will be exercisable for one Resulting Issuer Share at the Issue Price of the Subscription Receipts.

The Subscription Receipts will be offered in all provinces of Canada and such other jurisdictions as Awakn and the Co-Lead Agents may agree, where the Concurrent Financing can be offered and sold without the requirement to file a prospectus or similar document. It is expected that the net proceeds from the Concurrent Financing will be used for clinic openings, research and development, general and administration, and general working capital.

The Subscription Receipts issued in the Concurrent Financing will be subject to a statutory four month hold period. Upon completion of the Proposed Transaction and satisfaction of the Release Conditions, the Resulting Issuer Shares will not be subject to any hold period under applicable Canadian securities laws.

Closing of the private placement is subject to negotiation and execution of definitive documentation.

The Resulting Issuer

Upon completion of the Proposed Transaction, the Resulting Issuer will carry on the business of Awakn, which is a biotechnology company with clinical operations, researching, developing, and delivering psychedelic medicine to treat addiction and other mental health conditions.

Subject to applicable shareholder and NEO approval, upon completion of the Proposed Transaction, the board of directors and management of the Resulting Issuer will be comprised of the following individuals:

Anthony Tennyson, President, Chief Executive Officer, Director

Mr. Tennyson is an experienced professional and financial services industry executive, with over 15 years Risk Consulting and Capital Markets experience. Prior to co-founding Awakn Life Sciences, Anthony worked at Aon plc, a leading global professional services firm providing a range of risk, reinsurance, and health solutions, for 10 years holding a range of senior strategy and commercial roles. Anthony was global head of operations and strategy for Aon’s risk consulting division and Anthony also led Aon’s Energy and Financial Institutions risk consulting practice groups globally. Prior to Aon, Anthony worked in capital markets for five years with both Merrill Lynch and Bank of Ireland. Anthony holds an MBA in specializing in Strategy and Finance and an MSc in Technology both from University College Dublin’s Smurfit Graduate School of Business, Ireland’s top ranked business school.

Jonathan Held, Chief Financial Officer and Secretary

Mr. Held, CPA, CA, is a seasoned financial executive with CFO level experience for private / public companies. Mr. Held is a partner at ALOE Finance, a boutique firm specializing in transaction advisory and senior level finance solutions. Mr. Held has worked in a number of sectors including technology, biotech and natural resources, both domestic and international, and has been involved in numerous successful public market transactions including initial public offerings, reverse takeovers and financings. Mr. Held was previously a Director and Chief Financial Officer of Tassili Life Sciences Corp. which focused on mTBI and PTSD research. Mr. Held holds a Bachelor of Mathematics and Masters of Accounting from the University of Waterloo.

Dr. Benjamin Sessa, Chief Medical Officer and Director

Dr. Sessa MBBS (MD) BSc MRCPsych is a consultant child and adolescent psychiatrist who has worked with young people and adults in the field of addictions and trauma-related psychiatry for over 20 years. For the last 15 years Ben has been at the forefront of psychedelic research in the UK through his affiliations with Bristol University and Imperial College London, alongside of Professor David Nutt. He has taken part as a study doctor and as a healthy subject both receiving and administering MDMA, psilocybin, LSD, DMT and ketamine in multiple UK research studies. He ran one of the first UK-based medical cannabis prescribing clinics, having written over 500 prescriptions for medical cannabis. Ben is the Chief Medical Officer at Awakn Life Sciences, a company opening Europe’s first psychedelic medical clinic, providing psychedelic psychotherapy with ketamine for a wide range of psychiatric indications. Ben is an approved and registered MDMA and psilocybin therapist. He has led research into MDMA-assisted therapy for Alcohol Use Disorder and continues to carry out research in this area. Ben has been delivering keynote talks at international conferences in the psychedelic community for over 15 years and is also developing psychedelic therapist training courses as part of his role at Awakn Life Sciences. Ben is the co-founder and former president of Europe’s largest psychedelic conference, Breaking Convention.

James Collins, Chief Operating Officer

Mr. Collins is a senior business leader and mental health champion with 17 years of experience with Accenture Strategy, 7 years as Managing Director, designing and delivering corporate, digital and operating model strategies. James is an industry thought leader with several publications on digital innovation and the transformation of industries, including major studies in collaboration with the World Economic Forum. While at Accenture James was a champion for Inclusion, Diversity & Mental Health driving awareness and structural change to address inequity in the workplace. James holds a BSc and MPhil in Psychology from University College London (UCL), and a Foundation Certificate in Psychotherapy, Counselling & Coaching from the New School of Psychotherapy and Counselling (NSPC).

Shaun McNulty, Chief Science Officer

Dr. McNulty is an experienced drug development expert who has worked in and consulted for pharmaceutical and biotechnology companies for over 25 years. After obtaining a D.Phil. in CNS cell signaling from the University of York, he undertook post-doctoral studies at the University of Cambridge, researching neuronal cell signaling and molecular regulation of circadian physiology. Dr. McNulty’s industrial career began managing research and drug development teams and projects first for Pfizer and then for GSK Neuroscience departments. Dr. McNulty then moved into the biotechnology sector, managing portfolios and product development activities for both Syntaxin and ImmBio. Shaun went on to lead all research and drug development activities for Biosceptre and Inflection Biosciences as CSO. His career has focused on the identification, development and translation of innovative therapeutics, from target identification and characterization, to obtaining regulatory clearance for and managing clinical trials.

George Scorsis, Chairman of the Board

Mr. Scorsis has over 25 years of experience leading companies in highly regulated industries to rapid growth, including alcohol, energy drinks and, most recently, medical cannabis. While attending York University, completing his Bachelor in Administrative Studies, Mr. Scorsis worked as a University Ambassador for Bacardi Canada and held several executive roles. Following York University, Mr. Scorsis obtained an MBA at Queens University. Mr. Scorsis, formerly President of Red Bull Canada, was instrumental in restructuring the organization from a geographical and operational perspective, growing the business to $150 million in revenue. He also worked closely with Health Canada on guidelines regulating the energy drink category. Mr. Scorsis also brings agricultural and technological experience from his time as President at Mettrum Health Corp., which was acquired for $473 million by Canopy Growth Corporation. Mr. Scorsis was also the CEO and Director of Liberty Health Sciences Inc., which was one of the first Canadian cannabis companies to expand into the United States. He also served as Chairman of the Board of Directors of Scythian Biosciences Corp., a research and development company committed to advancing treatment efforts for traumatic brain injury with its proprietary cannabinoid-based combination drug therapy and additional cannabis-related activities across the globe as well as the former Chairman of Tassili Life Sciences Corp. which focuses on PTSD research. Mr. Scorsis is currently the Executive Chairman of WeedMD Inc.

Stephen Page, Director

Mr. Page is an experienced healthcare executive and board member, having significant experience working with both the National Health Service (“NHS“), and private enterprises in the United Kingdom. Mr. Page worked in the NHS for fifteen years and was the first CEO of Oxleas NHS Trust from 1993 through 1998, which focused on mental health and learning difficulties. From 1998 to 2005, Mr. Page worked on the board of directors of a number of private sector companies, including Priory Healthcare and Nestor plc. In 2005, Mr. Page was the CEO of Acorn Care and Education, which he grew through acquisitions and organic growth to become a leading national provider of special needs education and foster care resulting in the eventual sale to the Ontario Teachers’ Pension Plan in 2010. Mr. Page currently consults within the health, social care and education industry and acts as an executive coach seeking to promote high quality leadership and management in the sector. Mr. Page also acts as the Chair of Sequence Care, New Reflections and Brain in Hand. Mr. Page holds an MBA from London Business School and a Business Studies Degree from Sheffield University.

John Papastergiou, Director

Professor Papastergiou is an experienced clinical research scientist and pharmacist. He has served as an advisor to many large pharmaceutical organizations including Bayer, Pfizer, GSK, and Astra Zeneca and he owns and operates four large community pharmacies in Canada. Prof. Papastergiou’s innovative research in the area of point-of-care diagnostic testing and pharmacogenomics has led to the development and advancement of a number of tech start-up companies of which he has sat on the board of directors. Prof. Papastergiou holds Faculty appointments at the schools of Pharmacy at each of the University of Toronto and the University of Waterloo. Prof. Papastergiou has won a number of awards including Canadian Pharmacist of the Year. In 2019, he was named by the International Forum on Advancement of Healthcare as one of the top 100 healthcare leaders globally and was also presented with the Ontario Pharmacists’ Association Award for Excellence in Research and Academia. Prof. Papastergiou holds multiple degrees including a PhD from Rhabdoud University, Netherlands. He is a sought after speaker, author, and media personality participating at events in over 30 countries.

Upon the completion of the Proposed Transaction, it is expected that Awakn shareholders will hold approximately 99% of the issued and outstanding Resulting Issuer shares on a non-diluted basis. Investors are cautioned that, except as disclosed in the Company’s management information circular to be prepared in connection with the Proposed Transaction, any information released or received with respect to the Proposed Transaction may not be accurate or complete and should not be relied upon. There can be no assurance that the Proposed Transaction will be completed as proposed or at all.

Awakn Initiates New Chemical Entity Program With Evotec And David Nutt

Defining clear development pathway for next generation of psychedelic medicines to treat addiction

Awakn announces today the initiation of a new chemical entity (NCE) development program to strengthen Awakn’s pipeline for the treatment of a broad range of addictions. The Company has also announced the appointment of Evotec as NCE research partner and the selection of Prof. David Nutt, one of the world’s leading experts on addiction, as program lead.

This announcement follows Awakn’s March 2021 acquisition of a significant body of proprietary research from Equasy Enterprises, including details of newly discovered actions of MDMA (Equasy Acquisition).

Awakn will build on its position and experience as a clinical phase biotechnology company to develop a range of innovative and targeted new candidates to treat several poorly addressed addictions. Awakn will focus on addictions where the consequences for the patient, their family and society are at present severe.

The selection of Evotec as NCE research partner, combined with the appointment of Prof. David Nutt, and the Equasy Acquisition will significantly expedite the identification and characterization stages of Awakn’s program to develop the next generation of psychedelic medicines to treat Addiction and will position Awakn at the forefront of the emerging psychedelic biotechnology industry.

Professor David Nutt commented, “The molecules we are targeting will bring together the best therapeutic characteristics of MDMA; will have a more rapid onset of activity, and a short half-life, in a research space where we expect to secure patent protection and have freedom to operate.

Our ambition is to fully integrate effective psychedelic-based treatment into mainstream healthcare to better treat Addiction” said Anthony Tennyson, Awakn’s CEO. “Some of the world’s leading research data now lies with us, we have a clinical team with unparalleled experience in treating addiction, and now the appointment of a leading global research partner will significantly speed up this process.”

Awakn Announces Two Key Appointments to Its Board of Directors

Awakn announces the appointment of Stephen Page and Professor John Papastergiou as independent non-executive directors to the company’s Board of Directors. Adding significant pharmaceutical and healthcare sector experience and independent board governance to Awakn.

Stephen Page has worked in executive and Board of Director roles in the UK healthcare industry for over 30 years, most notably leading Priory Healthcare, the largest network of mental healthcare hospitals and clinics in the UK, through a period of rapid expansion and market dominance. He has led and successfully grown organizations in both public and private sectors including Oxleas NHS Trust in London (which focused on mental health), Nestor plc and Acorn Care and Education.

As founding CEO of Acorn Care and Education, and supported by Phoenix Equity Partners, Steve built the company via acquisition and organic growth to be a leading national provider of special needs education and foster care. He led the sale to the Ontario Teachers’ Pension Plan in 2010.

Professor Papastergiou is an experienced pharmacist and clinical research scientist who has served as an advisor to several leading pharmaceutical organizations including Bayer, Pfizer, GSK, and Astra Zeneca. His innovative research in point-of-care diagnostic testing and pharmacogenomics has led to the development and advancement of several tech start-up companies of which he also served as a board director.

Professor Papastergiou holds Faculty appointments at the schools of Pharmacy at the University of Toronto and the University of Waterloo. In 2019, he was named by the International Forum on Advancement of Healthcare as one of the top 100 healthcare leaders globally and was also presented with the Ontario Pharmacists’ Association Award for Excellence in Research and Academia. 

“We are pleased to welcome both Steve and John’s significant experience and independent governance to our Board of Directors at this next stage of Awakn’s evolution,” said George Scorsis, Awakn’s Chairman. “Both are highly respected and have extensive experience in up-scaling fast-growing companies in the mental health and biotechnology sectors, respectively. We look forward to their assistance in guiding us towards our objectives to develop and deliver psychedelics and psychedelic-assisted psychotherapy to radically change mental health services and deliver significantly better patient outcomes.”

Awakn Announces Two Key Appointments to Its Board of Directors

Awakn announces the appointment of Stephen Page and Professor John Papastergiou as independent non-executive directors to the company’s Board of Directors. Adding significant pharmaceutical and healthcare sector experience and independent board governance to Awakn.

Stephen Page has worked in executive and Board of Director roles in the UK healthcare industry for over 30 years, most notably leading Priory Healthcare, the largest network of mental healthcare hospitals and clinics in the UK, through a period of rapid expansion and market dominance. He has led and successfully grown organizations in both public and private sectors including Oxleas NHS Trust in London (which focused on mental health), Nestor plc and Acorn Care and Education.

As founding CEO of Acorn Care and Education, and supported by Phoenix Equity Partners, Steve built the company via acquisition and organic growth to be a leading national provider of special needs education and foster care. He led the sale to the Ontario Teachers’ Pension Plan in 2010.

Professor Papastergiou is an experienced pharmacist and clinical research scientist who has served as an advisor to several leading pharmaceutical organizations including Bayer, Pfizer, GSK, and Astra Zeneca. His innovative research in point-of-care diagnostic testing and pharmacogenomics has led to the development and advancement of several tech start-up companies of which he also served as a board director.

Professor Papastergiou holds Faculty appointments at the schools of Pharmacy at the University of Toronto and the University of Waterloo. In 2019, he was named by the International Forum on Advancement of Healthcare as one of the top 100 healthcare leaders globally and was also presented with the Ontario Pharmacists’ Association Award for Excellence in Research and Academia. 

“We are pleased to welcome both Steve and John’s significant experience and independent governance to our Board of Directors at this next stage of Awakn’s evolution,” said George Scorsis, Awakn’s Chairman. “Both are highly respected and have extensive experience in up-scaling fast-growing companies in the mental health and biotechnology sectors, respectively. We look forward to their assistance in guiding us towards our objectives to develop and deliver psychedelics and psychedelic-assisted psychotherapy to radically change mental health services and deliver significantly better patient outcomes.”

Awakn Initiates New Chemical Entity Program With Evotec And David Nutt

Defining clear development pathway for next generation of psychedelic medicines to treat addiction

Awakn announces today the initiation of a new chemical entity (NCE) development program to strengthen Awakn’s pipeline for the treatment of a broad range of addictions. The Company has also announced the appointment of Evotec as NCE research partner and the selection of Prof. David Nutt, one of the world’s leading experts on addiction, as program lead.

This announcement follows Awakn’s March 2021 acquisition of a significant body of proprietary research from Equasy Enterprises, including details of newly discovered actions of MDMA (Equasy Acquisition).

Awakn will build on its position and experience as a clinical phase biotechnology company to develop a range of innovative and targeted new candidates to treat several poorly addressed addictions. Awakn will focus on addictions where the consequences for the patient, their family and society are at present severe.

The selection of Evotec as NCE research partner, combined with the appointment of Prof. David Nutt, and the Equasy Acquisition will significantly expedite the identification and characterization stages of Awakn’s program to develop the next generation of psychedelic medicines to treat Addiction and will position Awakn at the forefront of the emerging psychedelic biotechnology industry.

Professor David Nutt commented, “The molecules we are targeting will bring together the best therapeutic characteristics of MDMA; will have a more rapid onset of activity, and a short half-life, in a research space where we expect to secure patent protection and have freedom to operate.

Our ambition is to fully integrate effective psychedelic-based treatment into mainstream healthcare to better treat Addiction” said Anthony Tennyson, Awakn’s CEO. “Some of the world’s leading research data now lies with us, we have a clinical team with unparalleled experience in treating addiction, and now the appointment of a leading global research partner will significantly speed up this process.”

Awakn Launches Digital Unit and Signs Agreement with the University of Exeter

First project to use advanced analytics to explore identity shifts in alcohol addiction

Awakn launches ‘Awakn Digital’, a new unit focused on using advanced analytics to improve the effectiveness of Psychedelic-Assisted Psychotherapy in treating Addiction. Awakn deepened its partnership with the University of Exeter to apply the latest developments in digital, technology and innovation in healthcare to tackle addiction.

Awakn previously announced an exclusive license to use and deliver the ‘Ketamine in the Reduction of Alcoholic Relapse’ (KARE) psychotherapy intervention, as validated in a Phase II clinical trial led by the University of Exeter.

The new agreement further deepens the partnership between Awakn and the University of Exeter by establishing a framework for the two organisations to work together to use advanced data analytics to improve the effectiveness of ketamine-assisted psychotherapy in treating addiction.

The first project will use a pattern classifier to detect identity shifts following ketamine treatment in Awakn clinics. The project builds on the work of Dr Koschate-Reis who holds an EPSRC Innovation Fellowship “Psychological Identity in a Digital World” and has been working on developing digital signatures of identity shift in recovery in people with problematic substance use in collaboration with local drug and alcohol services.

Prof. Celia Morgan, Head of Psychology, Professor of Psychopharmacology, University of Exeter will lead the project.

Prof. Celia Morgan stated, “By using an advanced data analytics approach in our work with Awakn, we aim to develop a richer understanding of the process of change following psychedelic treatment. The insights gained will allow us to transform and target our treatments to maximise their effectiveness for each and every patient.”

Anthony Tennyson, Awakn Chief Executive Officer, stated, “We are delighted to be deepening our relationship with the University of Exeter. There is a significant gap between patient need and effective addiction treatment solutions in the UK. Ketamine-assisted psychotherapy has demonstrated early promise in being an effective treatment option for some patients. We are looking forward to assessing how advanced data analytics can improve the effectiveness of this treatment option and improve patient outcomes in the UK.”

Awakn Launches Digital Unit and Signs Agreement with the University of Exeter

First project to use advanced analytics to explore identity shifts in alcohol addiction

Awakn launches ‘Awakn Digital’, a new unit focused on using advanced analytics to improve the effectiveness of Psychedelic-Assisted Psychotherapy in treating Addiction. Awakn deepened its partnership with the University of Exeter to apply the latest developments in digital, technology and innovation in healthcare to tackle addiction.

Awakn previously announced an exclusive license to use and deliver the ‘Ketamine in the Reduction of Alcoholic Relapse’ (KARE) psychotherapy intervention, as validated in a Phase II clinical trial led by the University of Exeter.

The new agreement further deepens the partnership between Awakn and the University of Exeter by establishing a framework for the two organisations to work together to use advanced data analytics to improve the effectiveness of ketamine-assisted psychotherapy in treating addiction.

The first project will use a pattern classifier to detect identity shifts following ketamine treatment in Awakn clinics. The project builds on the work of Dr Koschate-Reis who holds an EPSRC Innovation Fellowship “Psychological Identity in a Digital World” and has been working on developing digital signatures of identity shift in recovery in people with problematic substance use in collaboration with local drug and alcohol services.

Prof. Celia Morgan, Head of Psychology, Professor of Psychopharmacology, University of Exeter will lead the project.

Prof. Celia Morgan stated, “By using an advanced data analytics approach in our work with Awakn, we aim to develop a richer understanding of the process of change following psychedelic treatment. The insights gained will allow us to transform and target our treatments to maximise their effectiveness for each and every patient.”

Anthony Tennyson, Awakn Chief Executive Officer, stated, “We are delighted to be deepening our relationship with the University of Exeter. There is a significant gap between patient need and effective addiction treatment solutions in the UK. Ketamine-assisted psychotherapy has demonstrated early promise in being an effective treatment option for some patients. We are looking forward to assessing how advanced data analytics can improve the effectiveness of this treatment option and improve patient outcomes in the UK.”

Psychedelic Molecule Development Data Acquired by Awakn from Prof. David Nutt

Prof. Nutt appointed Head of Research to Lead Awakn’s Next-Gen Psychedelic Molecule Development

Awakn Life Sciences announces the acquisition of significant proprietary research data on next generation candidate MDMA and Ketamine molecules from Prof. David Nutt’s Equasy Enterprises. In addition to the acquisition of the data, Prof. Nutt has been appointed as Head of Research to lead Awakn’s next generation psychedelic molecule development programme.

This latest development adds significantly to Awakn’s already strong research programmes, with the world’s first Phase II b MDMA-Assisted Psychotherapy trial initiated and further research planned on Ketamine-Assisted Psychotherapy. This milestone is in addition to Awakn’s recently announced exclusive licence of the intellectual property from the world’s only phase IIab trial of ketamine for Alcohol Use Disorder from the University of Exeter.

Prof. Nutt, Head of Research and Chair of the Scientific Advisory Board, Awakn Life Sciences, states, “I have worked in novel psychopharmacological molecule development for many years and have completed over 5 years of research specifically on next generation MDMA and Ketamine candidate molecules. I am delighted to be able to bring the research forward, to lead this activity in Awakn, and to significantly accelerate the development of new compounds to better treat Addiction.”

Anthony Tennyson, CEO Awakn Life Sciences, comments, “This is another great step forward for Awakn. Adding Next-Gen Psychedelic Molecule Development to our already strong research division and soon to be launched UK and EU clinics platform positions us firmly in the top tier of this industry.”

Psychedelic Molecule Development Data Acquired by Awakn from Prof. David Nutt

Prof. Nutt appointed Head of Research to Lead Awakn’s Next-Gen Psychedelic Molecule Development

Awakn Life Sciences announces the acquisition of significant proprietary research data on next generation candidate MDMA and Ketamine molecules from Prof. David Nutt’s Equasy Enterprises. In addition to the acquisition of the data, Prof. Nutt has been appointed as Head of Research to lead Awakn’s next generation psychedelic molecule development programme.

This latest development adds significantly to Awakn’s already strong research programmes, with the world’s first Phase II b MDMA-Assisted Psychotherapy trial initiated and further research planned on Ketamine-Assisted Psychotherapy. This milestone is in addition to Awakn’s recently announced exclusive licence of the intellectual property from the world’s only phase IIab trial of ketamine for Alcohol Use Disorder from the University of Exeter.

Prof. Nutt, Head of Research and Chair of the Scientific Advisory Board, Awakn Life Sciences, states, “I have worked in novel psychopharmacological molecule development for many years and have completed over 5 years of research specifically on next generation MDMA and Ketamine candidate molecules. I am delighted to be able to bring the research forward, to lead this activity in Awakn, and to significantly accelerate the development of new compounds to better treat Addiction.”

Anthony Tennyson, CEO Awakn Life Sciences, comments, “This is another great step forward for Awakn. Adding Next-Gen Psychedelic Molecule Development to our already strong research division and soon to be launched UK and EU clinics platform positions us firmly in the top tier of this industry.”

Awakn acquires IP from a Phase II KAP Trial for AUD from the University of Exeter

Awakn intends to run a Phase III trial for ‘Ketamine-Assisted Psychotherapy for Alcohol Use Disorder’

Awakn announced today an exclusive license to use and deliver the ‘Ketamine in the Reduction of Alcoholic Relapse’ (KARE) psychotherapy intervention, as validated in a Phase II clinical trial led by the University of Exeter.

The KARE clinical research study, led by Prof. Celia Morgan of the University of Exeter, was a Phase II a/b, four-armed, placebo-controlled trial assessing ketamine combined with the KARE psychotherapy in the treatment for alcohol use disorder (AUD). The study started in 2016, finished in 2020 and included 96 participants, funded by the Medical Research Council. The primary endpoints of the Phase II trial were percentage days abstinent and relapse at 6 months, with secondary endpoints including depressive symptoms, craving, and quality of life.

The combined therapy arm, compared to other arms, demonstrated a clear capacity to improve the lives of people struggling with alcohol problems by reducing drinking over a six-month period.

Awakn also today announced that Prof. Celia Morgan will support Awakn’s activity in bringing the KARE research forward form Phase II to Phase III (subject to regulatory approval) and introducing evidence-based Ketamine-Assisted Psychotherapy for AUD into Awakn’s clinics as they open throughout the UK and EU.

Prof. Celia Morgan stated “It is a great milestone in Ketamine-Assisted Psychotherapy to take this novel evidence-based treatment forward both into the clinic and to a fully definitive Phase III trial. The Phase III study of Ketamine-Assisted Psychological therapy would be a world first in any patient group, and the first Phase III trial of ketamine in Alcohol Use Disorder.”

Dr. Ben Sessa, Awakn Chief Medical Officer, who recently announced results of the world’s first ‘MDMA in Alcohol Use Disorder’ clinical trial stated “Psychotherapy forms the bedrock of the way we use ketamine at Awakn, Celia Morgan’s cutting-edge research is the world’s first evidence-based approach combining ketamine with psychotherapy to treat Alcohol Use Disorder. In this post-COVID era there is no better time to be bringing this effective treatment approach to our patients struggling with alcohol use disorder.”