Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial
One in four young adults contemplated suicide last year.
Clearly, something needs to change. Could ketamine be the solution?
A study last month found that ketamine was well-tolerated in adolescents aged 13-17 and significantly reduced their depression symptoms.
76% of participants had at least a 50% reduction in depression scores within 3 days of receiving a ketamine infusion, compared to 35% of the placebo group.
The teens had tried between 1 and 7 antidepressants without success prior to the treatment. They all remained on their medications during the trial (SSRIs, non-SSRI antidepressants, mood stabilizers, or lithium) with no serious adverse side effects.