PharmAla Biotech contracts with InterVivo Solutions to validate novel MDMA analogs
Proof-of-concept preclinical animal research begun on PharmAla’s patented ABA series of non-scheduled MDXX compounds
VANCOUVER, March 3, 2022 (Canada Newswire) – PharmAla Biotech Holdings Inc. (“PharmAla” or the “Company”) (CSE: MDMA), a biotech company focused on the research, development and manufacturing of pharmaceuticals in the MDXX class, is pleased to announce that the Company has initiated preclinical research on a new class of patented novel chemical entities (NCEs) at InterVivo Solutions.
“PharmAla’s goal is to create novel drugs with improved toxicology profiles, and to expand use cases and indications for these drugs. PharmAla’s ABA series of drug candidates are based on a molecule in the MDXX class which is not scheduled as a controlled substance in Canada,” said Nick Kadysh, PharmAla’s CEO. “In InterVivo Solutions, we have found an excellent research partner to fast-track the research to select the most promising drug in the ABA series, and bring it forward to the Clinical phase.”
InterVivo Solutions is a well-established pre-clinical contract research organization (CRO) with expertise in neuropsychiatric and neurological diseases. Together with Transpharmation, they form the largest boutique Neuroscience -specialized small and large animal CRO. InterVivo Solutions will study PharmAla’s novel NCEs evaluating the molecules’ pharmacological effects and toxicology as compared to traditional, generic MDMA.
“InterVivo Solutions is proud to support the research efforts of PharmAla to develop novel entactogenic chemical entities with improved safety profiles. This safety-first approach will provide key insights that will not only de-risk their transition to clinical use, but also enhances our knowledge base and understanding of the key features of this disruptive class of molecules,” added Mark Duxon, CEO of InterVivo Solutions.
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About InterVivo Solutions/Transpharmation
Recently merged, InterVivo Solutions (IVS)/Transpharmation(TPH) is the world’s leading neuroscience contract research organization, offering translational research services with a focus on next-generation neuroscience drug discovery. IVS/TPH offers in vivo gold-standard pharmacological models, drug metabolism, pharmacokinetics and early safety research studies for a global network of biopharmaceutical clients.