Psilocybin-assisted therapy 4 times more effective than antidepressants

Psilocybin-assisted psychotherapy produces large, rapid, and sustained antidepressant effects

A clinical trial showed psilocybin-assisted therapy was 4 times more effective at treating major depressive disorder than antidepressant drugs. 27 participants with a long-term history of depression received 11 hours of therapy in addition to two full-day psilocybin-assisted therapy sessions, two weeks apart. Patients received the doses of psilocybin while lying on a couch with eyeshades and listening to music through headphones, and clinical monitors provided guidance and support throughout the experience. Four weeks after the treatment, 71% of participants saw at least a 50% reduction in depression scores, and 54% of participants were in remission from depression.

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