A single dose of psilocybin has a lasting therapeutic effect on migraine headache, according to a new placebo-controlled study
A double-blind, placebo-controlled study found that a single low dosage of psilocybin effectively reduced the severity of migraine pain and functional impairments in participants with frequent migraines. Participants reported that the therapeutic effect lasted for at least two weeks with no adverse side effects, supporting years of anecdotal reports that psilocybin eases migraine symptoms.