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Revive Therapeutics Signs MOU with Attwill Medical Solutions for Phase 3 Clinical Trial for Bucillamine in COVID-19

TORONTO, Aug. 14, 2020 – Revive Therapeutics Ltd. (“Revive” or the “Company”) (CSE: RVV, US: RVVTF), a specialty life sciences company focused on the research and development of therapeutics for medical needs and rare disorders, is pleased to announce that it has signed a Memorandum of Understanding (“MOU”) with Attwill Medical Solutions Sterilflow, LP (“AMS”) to establish AMS as a resource for clinical packaging and distribution for the Company’s Phase 3 clinical trial to evaluate the safety and efficacy of Bucillamine in patients with mild-moderate COVID-19.

“We are pleased to engage in formal discussions with Attwill Medical to assist us in the clinical packaging and distribution for our Phase 3 clinical study in COVID-19, as they have the resources and capabilities to execute on a number of activities that are critical to large-scale clinical studies,” said Michael Frank, CEO of Revive.

Based in Lodi, Wisconsin, AMS is one of the largest contract Lyophilization services facilities in the USA and recently announced a MOU with Vaxart, Inc. affirming the parties’ intent to establish AMS as a resource for lyophilization development and large scale manufacturing including tableting and enteric coating for Vaxart’s oral COVID-19 vaccine. AMS operates an FDA compliant facility with ISO 13485 2016 certification and operates under cGMP and specializes in the lyophilization and related processing of pharmaceutical intermediates, medical devices, nutraceuticals and nutritional ingredients and supplements.

The MOU outlines a proposed scope of work with the intention to form a collaboration between Revive and AMS in the area of clinical packaging.  The primary activities that AMS may perform for the Phase 3 clinical study in COVID-19 are analytical and stability studies, clinical supply chain management, storage, distribution and project management.

As AMS is a related party to the Company due to the fact that Bill Jackson, a director of Revive, is an insider of AMS, the MOU is deemed to be a “related party transaction” as defined under Multilateral Instrument 61-101—Protection of Minority Security Holders in Special Transactions (“MI 61-101”). The transaction with AMS is exempt from the formal valuation and minority shareholder approval requirements of MI 61-101 (pursuant to subsections 5.5(a) and 5.7(a)) as the fair market value of the consideration to be paid to AMS will not exceed 25% of the Company’s market capitalization.

Revive would also like to announce that it has commenced the process to have the Company’s common shares upgraded and quoted on the OTCQB® Market exchange in the United States. Commencement of trading through the facilities of the OTCQB® is subject to the fulfilment of the various regulatory requirements and completion of due diligence.

Moving to the OTCQB® in the United States will provide existing shareholders with an additional trading platform to the Canadian Securities Exchange in addition to introducing the Company to a broader range of retail and institutional investors that a U.S. listing provides.

About Revive Therapeutics Ltd.

Revive is a life sciences company focused on the research and development of therapeutics for infectious diseases and rare disorders, and it is prioritizing drug development efforts to take advantage of several regulatory incentives awarded by the FDA such as Orphan Drug, Fast Track, Breakthrough Therapy and Rare Pediatric Disease designations. Currently, the Company is exploring the use of Bucillamine for the potential treatment of infectious diseases, with an initial focus on severe influenza and COVID-19. With its recent acquisition of Psilocin Pharma Corp., Revive is advancing the development of Psilocybin-based therapeutics in various diseases and disorders. Revive’s cannabinoid pharmaceutical portfolio focuses on rare inflammatory diseases and the company was granted FDA orphan drug status designation for the use of Cannabidiol (CBD) to treat autoimmune hepatitis (liver disease) and to treat ischemia and reperfusion injury from organ transplantation. For more information, visit www.ReviveThera.com.

The Company is not making any express or implied claims that its product has the ability to eliminate or cure COVID-19 (SARS-2 Coronavirus) at this time.

For more information, please contact:

Michael Frank
Chief Executive Officer
Revive Therapeutics Ltd.
Tel: 1 888 901 0036
Email: mfrank@fbn.436.myftpupload.com
Website: www.revivethera.com

Neither the Canadian Securities Exchange nor its Regulation Services Provider have reviewed or accept responsibility for the adequacy or accuracy of this release.

Cautionary Statement

This press release contains ‘forward-looking information’ within the meaning of applicable Canadian securities legislation. These statements relate to future events or future performance. The use of any of the words “could”, “intend”, “expect”, “believe”, “will”, “projected”, “estimated” and similar expressions and statements relating to matters that are not historical facts are intended to identify forward-looking information and are based on Revive’s current belief or assumptions as to the outcome and timing of such future events. Forward looking information in this press release includes information with respect to the Offering, including the intended use of proceeds. Forward-looking information is based on reasonable assumptions that have been made by Revive at the date of the information and is subject to known and unknown risks, uncertainties, and other factors that may cause actual results or events to differ materially from those anticipated in the forward-looking information. Given these risks, uncertainties and assumptions, you should not unduly rely on these forward-looking statements. The forward-looking information contained in this press release is made as of the date hereof, and Revive is not obligated to update or revise any forward-looking information, whether as a result of new information, future events or otherwise, except as required by applicable securities laws. The foregoing statements expressly qualify any forward-looking information contained herein. Reference is made to the risk factors disclosed under the heading “Risk Factors” in the Company’s annual MD&A for the fiscal year ended June 30, 2019, which has been filed on SEDAR and is available under the Company’s profile at www.sedar.com.

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AIkido Pharma Inc. to Present at The LD 500 Virtual Conference

NEW YORK, Aug. 14, 2020 /PRNewswire/ — AIkido Pharma Inc. (Nasdaq: AIKI) (“AIkido” or the “Company”) today announced that it will be presenting at the LD 500 investor conference on Thursday, September 3, 2020 at 11:20 a.m. ET.  Anthony Hayes, CEO of AIkido Pharma Inc. will be presenting to a live audience.

(PRNewsfoto/AIkido Pharma Incorporated)

Register here: https://ld-micro-conference.events.issuerdirect.com/

“We have been waiting for this moment all year long. Due to COVID, it has been nearly impossible for physical conferences to even take place. I want to show the world that you can still learn, have a great time, and see some of the most unique companies in the capital markets today. All without having to step foot outside. For the first time, LD Micro is accessible to everyone, and we are honored to welcome you to one of the most trusted platforms in the space,” stated Chris Lahiji, Founder of LD.

The LD 500 will take place on September 1st through the 4th.

View AIkido Pharma’s profile here: http://www.ldmicro.com/profile/AIKI

Profiles powered by LD Micro — News Compliments of Accesswire

About AIkido

AIkido was initially formed in 1967 and is a biotechnology company with a diverse portfolio of small-molecule anti-cancer therapeutics.  The Company’s platform consists of patented technology from leading universities and researchers and we are currently in the process of developing an innovative therapeutic drug platform through strong partnerships with world renowned educational institutions, including The University of Texas at Austin and Wake Forest University. Our diverse pipeline of therapeutics includes therapies for pancreatic cancer, acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). In addition, we are constantly seeking to grow our pipeline to treat unmet medical needs in oncology.

About LD Micro

Back in 2006, LD Micro began with the sole purpose of being an independent resource to the microcap world.

What started as a newsletter highlighting unique companies, has transformed into the pre-eminent event platform in the space.

The upcoming “500” in September is the Company’s most ambitious project yet, and the first event that is accessible to everyone.

For those interested in attending, please contact David Scher at david@ldmicro.com or visit www.ldmicro.com for more information.

Contact:

Investor Relations:
Hayden IR
Brett Maas, Managing Partner
Phone: (646) 536-7331
Email: brett@haydenir.com
www.haydenir.com

AIkido:
Phone: 212-745-1373
Email: investorrelations@AIkido.com
www.AIkido.com

CisionView original content to download multimedia:http://www.prnewswire.com/news-releases/aikido-pharma-inc-to-present-at-the-ld-500-virtual-conference-301112317.html

SOURCE AIkido Pharma Inc.

News Provided by PR Newswire via QuoteMedia

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TRYP THERAPEUTICS PARTNERS WITH ALBANY MOLECULAR RESEARCH INC. TO MANUFACTURE A PROPRIETARY PSILOCYBIN-BASED DRUG

La Jolla, CA – August 13, 2020 – Tryp Therapeutics Inc. (“Tryp” or the “Company”), a clinical-stage pharmaceutical company developing therapeutics targeting diseases with high unmet medical needs, announced today it has entered into an agreement with Albany Molecular Research Inc. (“AMRI”), a leading global contract research, development and manufacturing organization, to provide research, development and cGMP manufacturing of a proprietary psilocybin active pharmaceutical ingredient (“API”) to support the clinical development of TRP-8802, TRP-8803 and TRP-8804 programs.

“Working with AMRI as our U.S.-based active pharmaceutical ingredient supplier is a critical component of our rapid clinical development strategy and we very pleased to have engaged them to support our neuropsychiatric programs. By working with AMRI, we are able to create additional intellectual property around the manufacture and use of our proprietary psilocybin API.” said Larry Norder, Vice President of Manufacturing of Tryp.  Mr. Norder further commented, “AMRI’s excellent industry reputation, size, and wealth of experience with manufacturing API under cGMP brings very high credibility to our efforts to develop psilocybin as a therapeutic for indications with high unmet medical needs.”

“AMRI is proud to support Tryp Therapeutics in their mission to address diseases with highly unmet needs through the rapid development and scale-up of a novel process to advance Psilocybin into human clinical trials,” said Christopher Conway, president, AMRI.  “We are leveraging our core expertise in process development and cGMP manufacturing to help progress Tryp’s clinical pipeline.”

About Tryp Therapeutics:

Tryp Therapeutics is a clinical stage drug development company led by a management team with extensive drug development experience that is advancing transformative medicines with existing clinical data and known safety profiles for diseases with no effective first-line treatments. The company is building a diversified portfolio of product candidates targeting neuropsychiatric and oncology indications with high unmet medical needs.

About AMRI

AMRI, a contract research development and manufacturing organization, partners with the pharmaceutical and biotechnology industries to improve patient outcomes and quality of life. AMRI’s team combines scientific expertise and market-leading technology to provide a complete suite of solutions in discovery, development, analytical services, and API and drug product manufacturing. www.amriglobal.com

Contact:
TRYP Therapeutics Inc.
James Kuo, MD, Chief Executive Officer
E: jkuo@trytherapeutics.com
T: 1-833-811-TRYP (8797)

Forward Looking Statements
Certain statements in this press release may constitute forward-looking information. All statements other than statements of historical fact contained in this press release, including, without limitation, those regarding Tryp’s future, strategy, plans, objectives, goals and targets, and any statements preceded by, followed by or that include the words “believe”, “expect”, “aim”, “intend”, “plan”, “continue”, “will”, “may”, “would”, “anticipate”, “estimate”, “forecast”, “predict”, “project”, “seek”, “should” or similar expressions or the negative thereof, are forward-looking statements. These statements are not historical facts but instead represent only Tryp’s expectations, estimates and projections regarding future events. These statements are not guaranteeing future performance and involve assumptions, risks and uncertainties that are difficult to predict. Therefore, actual results may differ materially from what is expressed, implied or forecasted in such forward-looking statements. The forward-looking information and forward-looking statements included in this press release are made as of the date of this press release. The Company does not undertake an obligation to update such forward-looking information or forward-looking information to reflect new information, subsequent events or otherwise unless required by applicable securities law.

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YIELD GROWTH ANNOUNCES NAME CHANGE AND PROVIDES CORPORATE UPDATE

August 13, 2020 – Vancouver, BC: The Yield Growth Corp. (CSE:BOSS) (OTCQB:BOSQF) (FE:YG3) (the “Company”) announces that it will be changing its corporate name to Better Plant Sciences Inc. to reflect its strategic focus on the fast-growing market for plant-based consumer products. The Company’s new stock symbol on the CSE will be “PLNT”, and the name change will be effective on Tuesday, August 18, 2020.

Since inception, all of the Company’s consumer product activities have been in the development and commercialization of all-natural, plant-based formulas. This began with the 2017 acquisition of a large plant-based formula library that includes skin care, personal care products, therapeutic products, beverages, edibles, topical wellness products, cleaning products, and a hand sanitizer – all developed under the guidelines of traditional Ayurvedic principles. The Company has also launched cannabis products through its Wright & Well brand in Oregon and has been working to develop the Jack & Jane line of cannabis products for Canada as well as medicinal mushroom products via its subsidiary, NeonMind Biosciences Inc. Continuing this momentum, the Company is committed to expanding its plant-based product portfolio across existing and new product categories and will continue to commercialize its extensive plant-based library of products.

“Herbal formulations based on traditional systems like Ayurveda have seen rapid growth in the past few years. We are committed to using the highest-quality, natural, plant-based ingredients in all of our products,” said CEO Penny White. “The name Better Plant Sciences is highly aligned with our mission, and positions us to capitalize on the growth in consumer demand for plant-based alternatives across all categories. We want to make it easy for consumers to make better choices for their health by making better products and holding ourselves to the highest standard to be a better company.”

The Company has put significant resources into fostering the growth of its direct-to-consumer business to drive sales, including the recent transfer of its Urban Juve e-commerce site onto Shopify as well as ensuring that products are also available on Amazon.ca. Creating product listings for U.S.-based consumers on Amazon.com is the next step in the Company’s direct-to-consumer sales focus.

“We have made the decision to focus solely on driving sales within Canada and the U.S. for the foreseeable future, as the COVID-19 pandemic has made those distribution channels a more reliable option. COVID-19 has also changed the outlook for retail channels worldwide and our strategy reflects this,” added White.

The Company has also been highly focused on developing the scalability of its operations while ensuring they remain true to its natural wellness and sustainability values. The company has stability tested more than 50 product formulations to ensure a 2-year shelf life for its products using plant-based preservatives. Cost-effective and environmentally friendly packaging solutions have also been sourced by the company.

“We strive to ensure our corporate practices are good to our people, customers, shareholders, employees, and our planet. Plant-based products made with high-quality natural and sustainable components, formulated to help our customers achieve optimal wellness is a crucial aspect of our business,” said White. “For our shareholders, we have ensured that we remain dedicated to staying on top of emerging trends and societal changes in order to stay relevant and set up our products for success. For employees, we offer a flexible, creative workplace, enabling remote work options that enable a healthy work-life balance.”

The new name and new symbol are intended to capture everything the Company has been developing thus far and what it plans to achieve moving forward: to make plant-based products and support wellness for a better life.

 

About The Yield Growth Corp.

The Yield Growth Corp. (CSE: BOSS), (OTCQB: BOSQF)  is a phytoceutical and consumer packaged goods company that develops and acquires intellectual property and other assets related to plant-based products and therapeutics, and develops, manufactures, markets, sells and distributes plant-based products that improve lives. It has over 200 proprietary wellness formulas at various stages of commercialization, including over 20 products that are now for sale through  e-commerce or brick and mortar retail stores. It has 14 patent applications filed in what the Global Wellness Institute reports is a $4.2 trillion-dollar global wellness market.  Its majority owned subsidiary NeonMind Biosciences Inc. is launching a line of medicinal mushroom products and is developing intellectual property in the emerging area of psychedelic medicine.  The Yield Growth management team has deep experience with global brands including Johnson & Johnson, Procter & Gamble, Skechers and Aritzia.

 

Investor Relations Contacts:

Penny White, President & CEO

Kevan Matheson, Investor Relations

invest@yieldgrowth.com

1-833-514-BOSS   1-833-514-2677

1-833-515-BOSS   1-833-515-2677

The Canadian Securities Exchange has not reviewed, approved or disapproved the contents of this news release.

 

Cautionary Statement Regarding Forward-Looking Statements

This press release includes forward-looking information and statements (collectively, “forward looking statements”) under applicable Canadian securities legislation.  Forward-looking statements are necessarily based upon a number of estimates, forecasts, beliefs and assumptions that, while considered reasonable, are subject to known and unknown risks, uncertainties, and other factors which may cause actual results and future events to differ materially from those expressed or implied by such forward-looking statements.  Such risks, uncertainties and factors include, but are not limited to: risks related to the development, testing, licensing, brand development, availability of packaging, intellectual property protection, reduced global commerce and reduced access to raw materials and other supplies do to the spread of the Coronavirus, the potential for not acquiring any rights as a result of the patent  application and any products making use of the intellectual property may be ineffective or the company may be unsuccessful in commercializing them; and other approvals will be required before commercial exploitation of the intellectual property can happen.  Demand for the company’s products, general business, economic, competitive, political and social uncertainties, delay or failure to receive board or regulatory approvals where applicable, and the state of the capital markets.  Yield Growth cautions readers not to place undue reliance on forward-looking statements provided by Yield Growth, as such forward-looking statements are not a guarantee of future results or performance and actual results may differ materially. The forward-looking statements contained in this press release are made as of the date of this press release, and Yield Growth expressly disclaims any obligation to update or alter statements containing any forward-looking information, or the factors or assumptions underlying them, whether as a result of new information, future events or otherwise, except as required by law.

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MindMed Expanding R&D in Europe, Appoints Dr. Miri Halperin Wernli As President

BASEL, Switzerland, Aug. 13, 2020 /PRNewswire/ — Mind Medicine (MindMed) Inc. (NEO: MMED OTCQB: MMEDF) is expanding its presence in Europe. The leading neuro-pharmaceutical company for psychedelic inspired medicines will open an operating subsidiary in Switzerland that will oversee clinical development, scientific collaborations and the expansion of MindMed’s business in Europe. As part of the ramp up and planning process for its growing global pipeline of clinical programs of psychedelic inspired medicines, MindMed’s board of directors has appointed Dr. Miri Halperin Wernli as President to help guide MindMed’s clinical development strategy and provide further leadership to its R&D pipeline.

Dr. Halperin Wernli will be tasked with expanding the clinical and scientific team in Europe. Her immediate primary leadership responsibilities center around the company’s LSD microdosing program and Project Lucy, the LSD experiential therapy program for anxiety disorders. Dr. Halperin Wernli will also help implement R&D collaborations in Europe which include the company’s partnership with the University Hospital Basel’s Liechti Lab.

Dr. Miri Halperin Wernli said: “I am very excited to help scale MindMed’s R&D as we seek to prove to governments and society that psychedelic inspired medicines and therapies can play a vital role in addressing the growing global mental health and addiction crisis. I passionately believe psychedelic inspired medicines and therapies have immense potential to redefine society’s approach to mental health. Many mental health disorders appear to be interconnected which presents a unique opportunity to MindMed to innovate and create novel treatment paradigms for various severe and chronic mental health conditions which have poor and unsatisfactory therapeutic offerings at present.”

Dr. Halperin Wernli is a senior pharmaceutical and biomedical executive with over 30 years of strategic and operational leadership in the biopharmaceutical industry and a deep understanding of drug and product development in heavy regulated environments. Dr. Halperin Wernli has held worldwide senior leadership positions in product development, R&D and Strategic Marketing throughout Switzerland and in the United States at leading pharmaceutical companies including Merck, Sharp & Dohme, Roche, and Actelion Pharmaceuticals. In addition to her roles in drug development in the pharma industry, Dr. Halperin Wernli has a depth of clinical experience in child and adult psychiatry in hospital settings in Switzerland and Canada.

Dr. Halperin Wernli previously co-founded and led Creso Pharma, an Australian listed medical cannabis company with operations in Europe and Canada.

MindMed Co-Founder and Co-CEO JR Rahn said: “It is a real honor for our company to be able to welcome Dr. Halperin Wernli. She brings a wealth of experience, knowledge and leadership in our approach for patients and her expertise will help us to continue to pioneer the fast-growing psychedelic inspired medicine market.”

‍

About MindMed

Mind Medicine (MindMed) Inc. is a neuro-pharmaceutical company that discovers, develops and deploys psychedelic-inspired medicines to improve health, promote wellness and alleviate suffering. The company has initiated or is initiating studies to evaluate potential treatments to help patients with ADHD, anxiety, cluster headaches and substance abuse. The MindMed executive team brings extensive biopharmaceutical industry experience to this groundbreaking approach to the development of next-generation psychedelic medicines. MindMed trades on the NEO Exchange under the symbol MMED. MindMed can also be traded in the US under the symbol OTC: MMEDF and in Germany under the symbol DE:MMQ. For more information: www.mindmed.co.

MindMed Forward-Looking Statements

This press release includes forward-looking statements that involve risks and uncertainties relating to future events and performance of Mind Medicine (MindMed) Inc. (“MindMed”), and actual events or results may differ materially from these forward-looking statements. Words such as “anticipate,” “expect,” “intend,” “plan,” “believe,” “seek,” “estimate,” variations of such words, and similar expressions are intended to identify such forward-looking statements, although not all forward-looking statements contain these identifying words. These statements concern, and these risks and uncertainties include, among others, MindMed’s and its collaborators’ ability to continue to conduct research and clinical programs, MindMed’s ability to manage its supply chain, product sales of products marketed by MindMed and/or its collaborators (collectively, ” Products”), and the global economy; the nature, timing, and possible success and therapeutic applications of Products and Product candidates and research and clinical programs now underway or planned; the likelihood, timing, and scope of possible regulatory approval and commercial launch of Product candidates and new indications for  Products; unforeseen safety issues resulting from the administration of  Products and Product candidates in patients, including serious complications or side effects in connection with the use of MindMed’s Products and product candidates in clinical trials; determinations by regulatory and administrative governmental authorities which may delay or restrict MindMed’s ability to continue to develop or commercialize Products; ongoing regulatory obligations and oversight impacting  Products, research and clinical programs, and business, including those relating to patient privacy; uncertainty of market acceptance and commercial success of Products and Product candidates and the impact of studies  on the commercial success of Products and Product candidates; the availability and extent of reimbursement of Products from third-party payers, including private payer healthcare and insurance programs, health maintenance organizations, pharmacy benefit management companies, and government programs such as Medicare and Medicaid; competing drugs and product candidates that may be superior to Products and Product candidates; the extent to which the results from the research and development programs conducted by MindMed or its collaborators may be replicated in other studies and lead to therapeutic applications; the ability of MindMed to manufacture and manage supply chains for multiple products and product candidates; the ability of MindMed’s collaborators, suppliers, or other third parties (as applicable) to perform manufacturing, filling, finishing, packaging, labelling, distribution, and other steps related to MindMed’s Products and product candidates; unanticipated expenses; the costs of developing, producing, and selling products; the ability of MindMed to meet any of its financial projections or guidance and changes to the assumptions underlying those projections or guidance; the potential for any license or collaboration agreement to be cancelled or terminated without any further product success; and risks associated with intellectual property of other parties and pending or future litigation relating thereto, other litigation and other proceedings and government investigations relating to MindMed and its operations, the ultimate outcome of any such proceedings and investigations, and the impact any of the foregoing may have on MindMed’s business, prospects, operating results, and financial condition. Any forward-looking statements are made based on management’s current beliefs and judgment. MindMed does not undertake any obligation to update publicly any forward-looking statement.

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Field Trip Psychedelics Inc. Expands Stateside With Psychedelic-Enhanced Psychotherapy Clinic in New York City

Field Trip continues to usher in a new generation of effective treatments for mental health challenges with the opening of the New York location

NEW YORK, Aug. 13, 2020 /PRNewswire/ — Field Trip Psychedelics Inc. (“Field Trip” or the “Company”), the company redefining mental health and well-being through its ground-breaking work in psychedelics and psychedelic-enhanced psychotherapy, today announced that it is expanding stateside with the opening of a first-of-its-kind clinic in New York City. The clinic, opening under the Company’s Field Trip Health brand, exists to help people heal and overcome depression as well as other tough-to-beat mental health challenges through evidence-based, medically supervised psychedelic therapies.

Field Trip Health takes a step-by-step, integrated approach to using ketamine-enhanced psychotherapy to bring people on a path to mental wellness and healing. Evidence has shown that ketamine, a dissociative psychedelic that is also legal in the United states, is safe when administered in medically-supervised doses. Ketamine often provides rapid relief from symptoms of depression and other mental health conditions, and can create a period of neural plasticity through which people, with supportive therapies, experience improved well-being and healthier, more optimistic and more meaningful outlooks on life. Patients undergoing this therapy often see results after a single session.

“There is no better place to make our entry into the US than New York City. Known for the ‘Empire State of Mind,’ we’re excited for people here to experience the ‘Field Trip State of Mind,’ one filled with hope, optimism and wonder,” said Ronan Levy, Field Trip’s Executive Chairman. “With our Toronto clinic, we have demonstrated first-hand the transformative healing potential of psychedelics for people struggling with their mental health. Our expansion into New York gives us a unique opportunity to further demonstrate the power of psychedelic therapies, and help people in New York on their own personalized journey to healing.”

With setting playing a crucial role in the therapeutic experience of psychedelic-enhanced psychotherapy, Field Trip Health clinics are thoughtfully designed to be calm and inviting. Patient treatment is administered in a comfortable, spa-like environment that promotes tranquility and aids in the overall healing process.

“Our New York clinic includes Zen-inspired elements such as ikebana arrangements that are incorporated throughout the space to help patients ground and center themselves,” said Matt Emmer, Field Trip’s Director of Operations and Business Development, who oversaw the design and build of the New York clinic. “We created an intentional space and experience that is designed to touch people and create a resonance that we believe will promote healing. The addition of greenery and other natural elements serve to connect patients to their natural surroundings, from a custom-designed moss wall in the entryway to nature-inspired murals in each of the treatment rooms.”

The clinic also incorporates a red ochre handprint wall concept that is designed for patients to set their intentions at the start of their treatment and for closure at completion. Patients are invited to dip a hand in red ochre at each milestone moment to commemorate their journey. The wall also serves to inspire future patients embarking on the same transformative experience.

The Field Trip treatment program is an active process that spans over a 3-4 week engagement period, but can be accommodated to each patient’s schedule. Each Ketamine and Psychotherapy Exploratory session is 2-3 hours in length. Sessions are designed to get patients comfortable with the effects of the medicine and the psychedelic experience as a whole. Throughout a patient’s journey, the individual effect of the medicine will evolve and patients will go to deeper places in their therapy as they continue through the program.

“It’s a great testament to the Field Trip Health team that, despite the pandemic, we were able to complete the construction of the clinic and open its doors without significant delay in our expansion plans,” added Hannan Fleiman, President of Field Trip Health. “It is our second location that we have opened this year following the opening in Toronto. Our third location in Los Angeles is slated to open later this month, and many more will be opening across the US in the months and years to come.”

The New York clinic is located at 137 E. 25th St., 11th Floor, New York, NY 10010 and patients can book a consultation by phone (1-833-222-0084), email (nyc@fieldtriphealth.com) or online at https://www.fieldtriphealth.com/getstarted?l=new-york.

About Field Trip Psychedelics Inc.

Field Trip is the world’s first mental wellness company at the forefront of the scientific re-emergence of psychedelics and psychedelic-enhanced therapies. With Field Trip Health centres opening across North America, and advanced research on plant-based psychedelics through Field Trip Discovery, we help people, from those in treatment to those seeking accelerated personal growth, with a simple, evidence-based way to heal and heighten engagement with the world.

Learn more at https://fieldtriphealth.com

SOURCE Field Trip Health

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Vireo Health to Report Second Quarter 2020 Results on August 26, 2020

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Overview of the worsening opioid crisis in Canada

Overview of the worsening opioid crisis in Canada and how DMT can help

Written by Jessica Cadoch

Oxycodone, Codeine, Morphine and Heroin are all classified opiates. These substances are procedurally offered by medical experts as painkillers and seek to relieve patients from deep suffering.

However, these substances are also highly addictive, and there is no thorough protocol to get patients off these substances once their prescription runs out. As a result, thousands of patients grow reliant on these medicines. Often, These individuals turn to illicitly-obtained opiates to support their increasing dependence on prescription medications. These alternatives include synthetically manufactured substances, some of which are up to thousands of times more potent than commonly-prescribed opioids. North America’s deadly opioid crisis has dominated countless news headlines over the past few years, but maybe you didn’t know precisely where it was born.

Advertised as the first ‘minimally addictive’ opioid, OxyContin (manufactured by Purdue Pharmaceuticals) managed to surpass heroin abuse rates in 2004. By 2010, prescription opiates “became the most abused class of substances among US high school seniors (National Institute of Drug Abuse [NIDA] 2011)… Purdue Pharmaceutical paid $634 million in fines for criminal charges based on misrepresentation of Oxycontin’s addictive potential (Van Zee 2009)”.

In the last six months, in the face of the COVID-19 pandemic, we have seen a dramatic spike in opioid overdoses, adding more layers of destruction and devastation on an already isolated, uncertain, and grieving society due to the distancing measures, deaths and job losses that hallmarked this pandemic.

Overview of the worsening opioid crisis in Canada
Alberta’s EMS teams have responded to the spike in opioid use calls since the COVID-19 pandemic.

What is happening with opioid misuse in Canada?

Due to a culmination of factors that include closed borders, a subsequent dip in supply and a lack of availability to clean substances, opiate overdoses in Canada increased drastically during COVID-19 isolation mandates.

Ontario has reported a 25% rise in fatal overdoses. A severe spike in opioid-related deaths prompts warning that carfentanil, an analogue of the synthetic opioid, fentanyl, is present in Edmonton’s street drugs, and is reportedly 100 times more potent than fentanyl, 5,000 times more potent than heroin and 10,000 times more potent than morphine.

“We now know that carfentanil is circulating. It’s in injectables and smokables, both up and down. Don’t use alone, have naloxone nearby, use a fraction of your usual dose.” – StreetworksAB
Alberta’s EMS teams have responded to the spike in opioid use calls since the COVID-19 pandemic. Furthermore, after serious efforts to implement SIS (safe injections sites) in British Columbia, with a 39% increase in overdose deaths in April alone, they are bearing witness to a resurgence in the opioid crisis. Finally, in the Yukon, opioid-related overdoses have doubled in the last year. Unsurprisingly, Canada’s Chief Public Health Officer, Dr. Theresa Tam calls the current crisis an “increasing concern” and an “unintended negative consequence” from the pandemic response.

The opposite of addiction is believed by some not to be sobriety, but to be “connection.”

Canada’s opioid response options

Journalist and addiction specialist Johann Hari famously noted that the opposite of addiction is not sobriety, but connection.

Over the past 20 years, alongside the opioid crisis, there has been a resurgence in interest in researching the healing potentials of psychedelic substances such as MDMA, Psilocybin, and DMT to treat Addiction, PTSD, Depression, and end-of-life distress.

Upon quantifying a mystical experience and developing the Mystical Experiences Questionnaire, researchers at Johns Hopkins University, including Dr. Roland Griffiths, Dr. Matthew Johnson and Dr. Katherine MacLean, noted that psychedelic substances foster feelings of connection to others, nature, and the self.

Before the creation of this questionnaire, in 1960, philosopher Walter Stace examined the qualities of a mystical experience, noting that “the core experience of unity was “the essence of all mystical experience” (Stace 1960:132)” (MacLean et al. 2012, 722).

Suppose substance use disorders stem partly from a loss of connection to self and community, as Hari notes, and psychedelic substances can foster these feelings of attachment to others, nature and self. Why then is psychedelic-assisted therapy for the treatment of addiction not more widely available for the treatment of addiction?

Bringing psychedelic substances into the world of Western Biomedicine is a long and slow endeavour. Many researchers are pooling their efforts towards making psychedelic-assisted therapy more accessible to those suffering from substance misuse.

Entheon Biomedical believes that it is time that the narrative around psychedelic-assisted therapy takes a sharp turn away from the stigma. We are committed to the legal development of safe & effective psychedelic medicines, particularly DMT. DMT, the active ingredient in ayahuasca, is a psychedelic that is traditionally used in spiritual practices by indigenous communities of the Amazon basin. Our researchers are confident that DMT can be beneficial to those who are dependent on harmful substances.

Contrary to other psychedelic substances undergoing FDA clinical trials in the US, DMT’s psychedelic onset is typically very rapid and intense, beginning within two minutes. Isolating DMT could result in a drug that delivers a much shorter psychedelic experience than the four to eight-hour type a patient would expect with ayahuasca, psilocybin, or MDMA.

A shorter experience could open up psychedelic-assisted treatment to more people at a fraction of the cost. One of the issues at the forefront of clinical trials and expanded access programs for psychedelic-assisted therapy is the financial accessibility of this therapy. Psychedelic-assisted therapy sessions with MDMA or with psilocybin-containing mushrooms last anywhere between 4-7 hours. Within these protocols, it is mandatory to have two therapists present during the therapy session. To compensate two therapists for 4-7 hours is a costly endeavour.

By isolating DMT, it may be possible to achieve shorter-lasting psychedelic experiences, which could lessen the length of psychedelic-assisted therapy sessions without diminishing efficacy. By shortening a patient’s time in the clinic, we would undoubtedly minimize the cost of this safe, effective, yet challenging to access therapy. With the opioid crisis worsening in Canada and beyond, we grow even more hopeful that Entheon Biomedical’s findings will help lay the groundwork for a more effective and compassionate treatment for substance use disorder.

“Having lost my brother to opiate addiction, I can attest to the devastation and chaos brought on by opiate use. As the lethality of these substances rises, the efficacy of currently available treatments remains unchanged, and hundreds of lives are lost each month in British Columbia alone. There should be an acceleration of efforts to provide new solutions rooted in a better understanding of the causes of addiction.” —Timothy Ko, Entheon CEO

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Revive Therapeutics Advancing Drug Delivery Technology for Psychedelics

Developed Prototypes of Orally Dissolvable Thin Film For Psilocybin

TORONTO, Aug. 11, 2020 – Revive Therapeutics Ltd. (“Revive” or the “Company”) (CSE: RVV, US: RVVTF), a specialty life sciences company focused on the research and development of therapeutics for medical needs and rare disorders, is pleased to announce, further to its press release of June 12, 2020, that under its sponsored research partnership agreement entered with the  Reed Research Group out of the University of Wisconsin-Madison to evaluate novel formulations of psilocybin, the Company has received the first set of orally dissolvable thin film strips initially to be used to deliver psilocybin and subsequently additional psychedelic-derived medicines.

“We are very pleased about the progress we have achieved to date and this technical milestone for our drug delivery technology specifically in the development of an orally dissolvable thin film strip for psilocybin, which will be used in future human clinical studies,” said  Michael Frank, CEO of Revive.  “This is the first time that we have applied our drug delivery technology to oral thin films and we see great promise in delivering psychedelic-based medicines to treat various diseases and disorders that would benefit from such a delivery method and in partnering with life sciences companies seeking to add unique offerings in their product pipeline.  We look forward to unveil the final prototype in the coming weeks.”

The Company has identified tannin-chitosan composite of orally dissolvable thin films as the lead candidate for the development of a unique delivery platform for therapeutic doses (1-20mg) of psilocybin into the oral cavity.  There are a number of advantages and benefits of an orally dissolvable psilocybin thin film such as the rapid dissolving and onset of action to the bloodstream, the ease and convenience for patients to administer without the need of water, chewing or swallowing, the potential of improved therapeutic outcomes and efficacy for underserved diseases and disorders and the flexibility to create accurate dosing and tasteful options.

The orally dissolvable thin film prototypes will undergo further scientific testing through a broad range of studies including testing of different dosages from 1 mg to 20 mg, physio-chemical characterization (e.g. tensile strength of films) of composite materials,  dissolution and disintegration testing, and rate of psilocybin release from composites.

The drug delivery technology aims to deliver both synthetic and natural extract of psilocybin in a potential number of ways such as orally dissolvable thin films, topical gels, creams or ointments, oral or transdermal patches, oral dosages and foams. The delivery technology is a natural, non-toxic, biodegradable and biocompatible composite that combines a tannin material, which is derived from a plant group having antibacterial, antifungal, antioxidant and wound healing properties, and a chitosan material, which is derived from the crustacean group having blood-clotting and antimicrobial properties. The delivery technology has a rapid onset of action and controlled or sustained release potential capabilities and may allow combining multiple extracts from mushrooms in one formulation.

Revive would also like to announce that it has granted 6,000,000 stock options to an officer and director. Each option is exercisable at $0.33 per common share at any time until August 5, 2025.

About Revive Therapeutics Ltd.

Revive is a life sciences company focused on the research and development of therapeutics for infectious diseases and rare disorders, and it is prioritizing drug development efforts to take advantage of several regulatory incentives awarded by the FDA such as Orphan Drug, Fast Track, Breakthrough Therapy and Rare Pediatric Disease designations. Currently, the Company is exploring the use of Bucillamine for the potential treatment of infectious diseases, with an initial focus on severe influenza and COVID-19. With its recent acquisition of Psilocin Pharma Corp., Revive is advancing the development of Psilocybin-based therapeutics in various diseases and disorders. Revive’s cannabinoid pharmaceutical portfolio focuses on rare inflammatory diseases and the company was granted FDA orphan drug status designation for the use of Cannabidiol (CBD) to treat autoimmune hepatitis (liver disease) and to treat ischemia and reperfusion injury from organ transplantation. For more information, visit www.ReviveThera.com.

For more information, please contact:

Michael Frank
Chief Executive Officer
Revive Therapeutics Ltd.
Tel: 1 888 901 0036
Email: mfrank@fbn.436.myftpupload.com
Website: www.revivethera.com

Neither the Canadian Securities Exchange nor its Regulation Services Provider have reviewed or accept responsibility for the adequacy or accuracy of this release.

Cautionary Statement

This press release contains ‘forward-looking information’ within the meaning of applicable Canadian securities legislation. These statements relate to future events or future performance. The use of any of the words “could”, “intend”, “expect”, “believe”, “will”, “projected”, “estimated” and similar expressions and statements relating to matters that are not historical facts are intended to identify forward-looking information and are based on Revive’s current belief or assumptions as to the outcome and timing of such future events. Forward looking information in this press release includes information with respect to the Offering, including the intended use of proceeds. Forward-looking information is based on reasonable assumptions that have been made by Revive at the date of the information and is subject to known and unknown risks, uncertainties, and other factors that may cause actual results or events to differ materially from those anticipated in the forward-looking information. Given these risks, uncertainties and assumptions, you should not unduly rely on these forward-looking statements. The forward-looking information contained in this press release is made as of the date hereof, and Revive is not obligated to update or revise any forward-looking information, whether as a result of new information, future events or otherwise, except as required by applicable securities laws. The foregoing statements expressly qualify any forward-looking information contained herein. Reference is made to the risk factors disclosed under the heading “Risk Factors” in the Company’s annual MD&A for the fiscal year ended June 30, 2019, which has been filed on SEDAR and is available under the Company’s profile at www.sedar.com.