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Clearmind Medicine Launches Study for Binge Eating with The Hebrew University Using its Proprietary MEAI Compound

Clearmind Medicine Launches Study for Binge Eating with The Hebrew University Using its Proprietary MEAI Compound

‍Focus on the discovery and development of novel therapeutic strategies to treat obesity and its related metabolic disorders

TORONTO, Nov. 24, 2021 (GLOBE NEWSWIRE) — Clearmind Medicine Inc. (CSE: CMND, FSE: CWY0, OTC Pink: CMNDF), (“Clearmind” or the “Company”), a psychedelic medicine biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and undertreated health problems, is pleased to announce it has signed an agreement to fund a new research and development project with the Hebrew University of Jerusalem’s Obesity and Metabolism Laboratory, to evaluate the Company’s proprietary compound, MEAI’s direct effect on binge eating including food and water intakes as well as activity and metabolic parameters.

The study, which will be overseen by Prof. Joseph (Yossi) Tam, D.M.D., Ph.D., head of the Obesity and Metabolism Laboratory and Associate Professor of Pharmacology at the Hebrew University’s Institute for Drug Research, will focus on testing the potential of MEAI to treat binge eating and related behaviors, and will support the discovery and development of novel therapeutic strategies to safely treat obesity and its associated metabolic disorders.

Increasingly prevalent in developed nations, the conditions of being overweight and obese are a serious health concern as they contribute to so many other conditions, including heart disease, stroke, type 2 diabetes, fatty liver disease, and certain types of cancers, some of the leading causes of preventable, premature death in the US. The Center for Disease Control and Prevention estimates that about 74% of adults in the US are overweight1 and over 40% are considered obese2. According to a recent study published in 2020, this phenomenon is also accompanied with the high and rising costs of obesity to the US Health Care system at an estimated annual medical cost for the full non-institutionalized population of adults, in 2013, equaling $342.2 billion.

Adi Zuloff-Shani, Ph.D., CEO of Clearmind, commented on the announcement, “The medical community has yet to establish an effective therapeutic or preventative treatment for obesity, despite its increasing prevalence and severe negative impacts on the medical and economic health of people around the world. Clearmind has been able to demonstrate the positive influence MEAI has on binge behavior with regard to alcohol use, and our preliminary research indicates it may have a similar effect on metabolic disorders.”

Prof. Tam added, “I have spent my career exploring the biological mechanisms underlying obesity and the metabolic syndrome, intending to develop an effective drug therapy. After viewing the early data on MEAI, I am optimistic that this compound has the potential to be a building block for a real solution and look forward to working with the Clearmind team to advance our shared objective.”

The first phase of the three-stage study will focus on assessing the direct effect of MEAI on food and water intakes as well as its ability to modulate activity and metabolic parameters.

Following the initial screening, the study will evaluate MEAI’s efficacy as a therapeutic metabolic agent on a high-fat diet-induced obese mouse model, by measuring MEAI’s potential to treat obesity, hepatic injury, glycemic and hormonal imbalance. Lastly MEAI’s binge eating and drinking mitigating properties will be determined by comparison of cumulative food and sucrose preference, respectively.

About Clearmind Medicine Inc.

Clearmind is a psychedelic pharmaceutical biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and underserved health problems, including alcohol use disorder. Its primary objective is to research and develop psychedelic-based compounds and attempt to commercialize them as regulated medicines, foods or supplements.

The Company’s intellectual portfolio currently consists of four patent families. The first, “Binge Behavior Regulators”, has been granted in the U.S., Europe, China and India, with pending divisional applications in Europe and the U.S. The second, “Alcohol Beverage Substitute”, has been approved for a European patent, with pending applications in the U.S., China and India. The Company intends to seek additional patents for its compounds whenever warranted and will remain opportunistic regarding the acquisition of additional intellectual property to build its portfolio.

Shares of Clearmind are listed for trading on the Canadian Securities Exchange under the symbol “CMND“, the Frankfurt Stock Exchange under the symbol “CWYO” and on the OTC Pink under the symbol “CMNDF“.

For further information, please contact:
Investor Relations,
Email: invest@clearmindmedicine.com
Telephone: (778) 400-5347
General Inquiries,
Info@Clearmindmedicine.com
www.Clearmindmedicine.com

FORWARD-LOOKING STATEMENTS:

This news release may contain forward-looking statements and information based on current expectations. These statements should not be read as guarantees of future performance or results. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements. Such statements include discussion of the new research and development project with the Hebrew University of Jerusalem’s Obesity and Metabolism Laboratory and the benefits of product candidate. There is no certainty that any of these events will occur. Although such statements are based on management’s reasonable assumptions, there can be no assurance that such assumptions will prove to be correct. We assume no responsibility to update or revise them to reflect new events or circumstances.

Investing into early-stage companies inherently carries a high degree of risk, and investment into securities of the Company shall be considered highly speculative.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of the securities in any province in which such offer, solicitation or sale would be unlawful. The securities issued, or to be issued, under the Private Placement have not been, and will not be, registered under the United States Securities Act of 1933, as amended, and may not be offered or sold in the United States absent registration or an applicable exemption from registration requirements.

Neither the Canadian Securities Exchange (the “CSE”) nor its Regulation Services Provider (as that term is defined in the policies of the CSE) accepts responsibility for the adequacy or accuracy of this release.

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Clearmind Medicine to Pursue Dual Listing on Nasdaq

Clearmind Medicine to Pursue Dual Listing on Nasdaq

Toronto, Ontario, Nov. 22, 2021 (GLOBE NEWSWIRE) — Clearmind Medicine Inc. (CSE: CMND, FSE: CWY0, OTC Pink: CMNDF), (“Clearmind” or the “Company“), a psychedelic medicine biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and undertreated health problems, today announced that its board of directors has decided to pursue a dual listing on the Nasdaq Stock Market. Clearmind intends to file a registration statements with the U.S. Securities and Exchange Commission in the coming months. The Company’s common shares will continue to be traded on the Canadian Stock Exchange.

The board’s decision was made following a growing interest by U.S.-based investors, wishing to have easier accessibility to the Company’s stock.

About Clearmind Medicine Inc.

Clearmind is a psychedelic pharmaceutical biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and underserved health problems, including alcohol use disorder. Its primary objective is to research and develop psychedelic-based compounds and attempt to commercialize them as regulated medicines, foods or supplements.

The Company’s intellectual portfolio currently consists of four patent families. The first, “Binge Behavior Regulators”, has been granted in the U.S., Europe, China and India, with pending divisional applications in Europe and the U.S. The second, “Alcohol Beverage Substitute”, has been approved for a European patent, with pending applications in the U.S., China and India. The Company intends to seek additional patents for its compounds whenever warranted and will remain opportunistic regarding the acquisition of additional intellectual property to build its portfolio.

Shares of Clearmind are listed for trading on the Canadian Securities Exchange under the symbol “CMND”, the Frankfurt Stock Exchange under the symbol “CWYO” and on the OTC Pink under the symbol “CMNDF”.

For further information, please contact:
Investor Relations,
Email: invest@clearmindmedicine.com
Telephone: (778) 400-5347
General Inquiries,
Info@Clearmindmedicine.com
www.Clearmindmedicine.com

FORWARD-LOOKING STATEMENTS:

This news release may contain forward-looking statements and information based on current expectations. These statements should not be read as guarantees of future performance or results. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements. Such statements include pursuing a dual listing on the Nasdaq Stock Market, filing a registration statement with the U.S. Securities and Exchange Commission, that the Company’s common shares will continue to trade on the Canadian Securities Exchange, and that the Company intends to seek additional patents for its compounds whenever warranted and will remain opportunistic regarding the acquisition of additional intellectual property to build its portfolio. There is no certainty that any of these events will occur. Although such statements are based on management’s reasonable assumptions, there can be no assurance that such assumptions will prove to be correct. We assume no responsibility to update or revise them to reflect new events or circumstances.

Investing into early-stage companies inherently carries a high degree of risk, and investment into securities of the Company shall be considered highly speculative.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of, the securities in any state or province in which such offer, solicitation or sale would be unlawful. Any offers, solicitations or offers to buy, or any sales of securities will be made in accordance with applicable registration requirements.

Neither the CSE nor its Regulation Services Provider (as that term is defined in the policies of the CSE) accepts responsibility for the adequacy or accuracy of this release.

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Clearmind Medicine Announces Sponsorship of Wonderland Psychedelic Conference in Miami

Clearmind Medicine Announces Sponsorship of Wonderland Psychedelic Conference in Miami

Toronto, Ontario, November 8, 2021 – Clearmind Medicine Inc. (CSE: CMND, FSE:CWY0), (“Clearmind” or the “Company“), a psychedelic medicine biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and under treated health problems, announced today its participation at the Wonderland MiamiConference organized by Microdose.‍

Wonderland Miami Conference is the largest in-person conference in the psychedelic medicine industry. The conference will take place on November 8th and 9th at the Adrienne Arsht Center for Performing Arts in Miami. The conference will offer a unique in-person convergence of business, science, music, and emerging technologies.

Wonderland Miami by Microdose is also a thought-leadership platform and an opportunity to connect with influential leaders in science, policy, and business.

The speakers list includes Drs. Matthew Johnson, Robin Carhart-Harris, and Rick Doblin. Other featured speakers at the event include Mike Tyson, former professional boxer and undisputed heavyweight champion, who has advocated for the use of psychedelic drugs, as well as Lamar Odom, a two-time NBA Champion andOlympic Gold Medalist.

Clearmind Medicine team will introduce the company at the conference. To arrange a meeting, please contact: invest@clearmindmedicine.com

About Clearmind Medicine Inc.

Clearmind is a psychedelic pharmaceutical biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and underserved health problems, including alcohol use disorder. Its primary objective is to research and develop psychedelic-based compounds and attempt to commercialize them as regulated medicines, foods or supplements.

TheCompany’s intellectual portfolio currently consists of two patent families. The first, “Binge Behavior Regulators,” has been granted in the U.S.,Europe, China and India, with pending divisional applications in Europe and theU.S. The second, “Alcohol Beverage Substitute,” has been approved for aEuropean patent, with pending applications in the U.S., China and India. TheCompany intends to seek additional patents for its compounds whenever warranted and will remain opportunistic regarding the acquisition of additional intellectual property to build its portfolio.

Shares of Clearmind are listed for trading on the Canadian Securities Exchange under the symbol “CMND” and the Frankfurt Stock Exchange under the symbol “CWY0.”

 

For further information, please contact:

Investor Relations,

Email: invest@clearmindmedicine.com

Telephone: (778) 400-5347

General Inquiries,

Info@Clearmindmedicine.com

www.Clearmindmedicine.com

 

FORWARD-LOOKING STATEMENTS:

This news release may contain forward-looking statements and information based on current expectations. These statements should not be read as guarantees of future performance or results. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements.Such statements include submission of the relevant documentation within the required timeframe to the satisfaction of the relevant regulators and raising sufficient financing to complete the Company’s business strategy. There is no certainty that any of these events will occur. Although such statements are based on management’s reasonable assumptions, there can be no assurance that such assumptions will prove to be correct. We assume no responsibility to update or revise them to reflect new events or circumstances.

Investing into early-stage companies inherently carries a high degree of risk, and investment into securities of the Company shall be considered highly speculative.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of, the securities in any province in which such offer, solicitation or sale would be unlawful. The securities issued, or to be issued, under the Private Placement have not been, and will not be, registered under the United States Securities Act of 1933, as amended, and may not be offered or sold in the United States absent registration or an applicable exemption from registration requirements.

Neither the Canadian Securities Exchange (the “CSE”) nor its Regulation ServicesProvider (as that term is defined in the policies of the CSE) accepts responsibility for the adequacy or accuracy of this release.

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A better way to get drunk?

Clearmind Signs Development and Supply Agreement to Produce its Drug Candidate MEAI Psychedelic Molecule With Aragen Life Sciences

This psychedelic makes you feel drunk. Could it be used to treat alcoholism?

5-Methoxy-2-aminoindane (MEAI) is a synthetic molecule that simulates the euphoric feeling of alcohol while reducing the desire to drink.

Pre-clinical studies conducted by Clearmind Medicine Inc. (CMND) show promising evidence that MEAI could treat alcohol use disorder (AUD) and binge drinking. Clinical trials expected to begin in the second half of 2022.

The company just signed a development and supply agreement with Aragen Life Sciences to manufacture the molecule.

PDF of article

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Clearmind Medicine Appoints Distinguished Addiction Experts Professor Wim van den Brink and Professor Gabriele Fischer to Its Scientific Advisory Board

Clearmind Medicine Appoints Distinguished Addiction Experts Professor Wim van den Brink and Professor Gabriele Fischer to Its Scientific Advisory Board

TORONTO, Ontario, Oct. 14, 2021 (GLOBE NEWSWIRE) — via InvestorWire — Clearmind Medicine Inc. (CSE: CMND) (FSE: CWY0) (“Clearmind” or the “Company“), a psychedelic medicine biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and under treated health problems, today announces that professors Wim van den Brink and Gabriele Fischer have joined the Company’s scientific advisory board.

Professor van den Brink, M.D., Ph.D., is a professor of addiction psychiatry at the Academic Medical Center of the University of Amsterdam and a recognized expert in the neurobiology and pharmacological treatment of substance use disorders and behavioral addictions. His work has garnered several prestigious awards, and his influence extends across policy and academics. He holds leadership positions on a myriad of professional committees and organizations, is a sought-after keynote speaker, has co-authored close to 800 peer-reviewed papers, and currently serves on the editorial boards of seven scientific journals in the fields of psychiatry and addiction.

Professor Gabriele Fischer, M.D., is a professor of addiction research and treatment, medical director of the Addiction Clinic at the Department of Psychiatry & Psychotherapy at the Medical University of Vienna, and has acted as principle or cooperating investigator on international epidemiological clinical and psychopharmacological studies in the field of substance use disorder and nonsubstance-related addictions. She is an influential thought leader in the treatment of addiction and is a long-standing consultant for many global organizations, including the United Nations Office on Drug and Crime (UNODOC), the World Health Organization (WHO) and the European Parliament. A prominent author and speaker, Fischer has given over 400 scientific presentations, authored over 150 peer-reviewed publications, and is involved in editorial and reviewing work for many international medical journals.

Adi Zuloff-Shani, Ph.D., CEO of Clearmind, commented on the appointments: “Professor van den Brink and professor Fischer have both made substantial contributions to the field of substance abuse and related behaviors, advancing the way we understand and treat addiction. There are few scientists in the world with their breadth of knowledge and experience, and we are delighted to welcome them to our scientific advisory board.”

About Professor Wim van den Brink, M.D., Ph.D.

Professor van den Brink is professor of addiction psychiatry at the Academic Medical Center of the University of Amsterdam and a recognized expert in the neurobiology and pharmacological treatment of substance use disorders and related comorbidities and behavioral addictions. He is president of the International Collaboration on ADHD and Substance Abuse, a member of the scientific advisory board Swiss Research Institute Public Health & Addiction and chair of the ZonMW program on mental health research.

His work has garnered numerous awards, including the Marie Curie Award for Neuroimaging of the Neurotoxicity of Ecstasy; Lifetime Achievement Award for Science from the Netherlands Association of Psychiatry; Honorable Member of the Spanish Society for Dual disorders; European Addiction Research Award from the European Federation of Addiction Societies (EUFAS); and, most recently, Doctor et Professor Honoris Causa at the Eötvös Loránd University in Budapest.

His influence extends across policy and academics and includes chairing the workgroups that developed the Dutch treatment guidelines for alcohol use disorders, opiate addiction and drugs other than opioids; the Scientific Program Committee of European College of Neuropsychopharmacology (ECNP); the advisory board Netherland Dialectical Behavioral Treatment; Netherlands National Quality Committee on Mental Health; and executive board Mainline Harm-Reduction.

A prolific writer, he is the co-author of more than 600 international peer-reviewed scientific papers. Until recently, he was an associate editor of Drug and Alcohol Dependence and chief editor of European Addiction Research and remains a member of the editorial boards of seven other psychiatric/addiction scientific journals.

Professor van den Brink received his medical degree from the Free University in Amsterdam and earned his Ph.D. at The State University of Groningen. During his tenure at the University of Amsterdam, he served as senior researcher, Dept. of Psychiatry; assistant professor of psychiatry; and professor of addiction psychiatry. He was also a Fellow Psychiatric Epidemiology at Columbia University in New York.

About Professor Gabriele Fischer

Professor Gabriele Fischer is a professor for psychiatry – addiction research and treatment; medical director of the Addiction Clinic, Department of Psychiatry & Psychotherapy at the Medical University of Vienna, a research facility and treatment center for patients with substance use disorders and nonsubstance dependence (e.g., pathological gamblers); and leader of the University’s Center for Public Health “Addiction in Public Health” project.

Professor Fischer has acted as principle or cooperating investigator on projects in the EU, the U.S. and Afghanistan regarding investigations on alternatives to coercive sanctions in patients with substance use disorders. Her work is typically focused on eliciting the views of key stakeholders from both health/welfare and justice sectors and advocates for early intervention, with an eye to not only increase the patient’s quality of life but also reduce societal costs.

Professor Fischer is a prominent author and speaker with more than 140 peer-reviewed publications and 400 presentations and is a member of multiple international scientific associations. Most noteworthy, she is a long-standing consultant for several international and national groups, including the United Nations Office on Drug and Crime (UNODOC), the World Health Organization (WHO) and the European Parliament. She is a member of the Scientific Board for Quality Control and Quality Management in Medicine and of the European Monitoring Center for Drugs and Drug addiction (EMCDDA), member of the General Medical Council in Austria, founding board member of Women for Women: Health Policy in Focus, and commission director of the Austrian Ombudsman Board dedicated to improving human rights in vulnerable populations.

About Clearmind Medicine Inc.

Clearmind is a psychedelic pharmaceutical biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and underserved health problems, including alcohol use disorder. Its primary objective is to research and develop psychedelic-based compounds and attempt to commercialize them as regulated medicines, foods or supplements.

The Company’s intellectual portfolio currently consists of two patent families. The first, “Binge Behavior Regulators,” has been granted in the U.S., Europe, China and India, with pending divisional applications in Europe and the U.S. The second, “Alcohol Beverage Substitute,” has been approved for a European patent, with pending applications in the U.S., China and India. The Company intends to seek additional patents for its compounds whenever warranted and will remain opportunistic regarding the acquisition of additional intellectual property to build its portfolio.

Shares of Clearmind are listed for trading on the Canadian Securities Exchange under the symbol “CMND” and the Frankfurt Stock Exchange under the symbol “CWY0.”

For further information, please contact:

Investor Relations,
Email: invest@clearmindmedicine.com
Telephone: (778) 400-5347

General Inquiries,
Info@Clearmindmedicine.com
www.Clearmindmedicine.com

FORWARD-LOOKING STATEMENTS:

This news release may contain forward-looking statements and information based on current expectations. These statements should not be read as guarantees of future performance or results. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements. Such statements include submission of the relevant documentation within the required timeframe to the satisfaction of the relevant regulators and raising sufficient financing to complete the Company’s business strategy. There is no certainty that any of these events will occur. Although such statements are based on management’s reasonable assumptions, there can be no assurance that such assumptions will prove to be correct. We assume no responsibility to update or revise them to reflect new events or circumstances.

Investing into early-stage companies inherently carries a high degree of risk, and investment into securities of the Company shall be considered highly speculative.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of, the securities in any province in which such offer, solicitation or sale would be unlawful. The securities issued, or to be issued, under the Private Placement have not been, and will not be, registered under the United States Securities Act of 1933, as amended, and may not be offered or sold in the United States absent registration or an applicable exemption from registration requirements.

Neither the Canadian Securities Exchange (the “CSE”) nor its Regulation Services Provider (as that term is defined in the policies of the CSE) accepts responsibility for the adequacy or accuracy of this release.

Wire Service Contact
InvestorWire (IW)
Los Angeles, California
www.InvestorWire.com
212.418.1217 Office
Editor@InvestorWire.com

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Clearmind Medicine Partners With Clinipace to Commence Processes Towards FDA Approval

Clearmind Medicine Partners With Clinipace to Commence Processes Towards FDA Approval

The Regulatory affairs and CRO will oversee the Company’s efforts to secure an IND review of MEAI as a potential treatment forAlcohol Use Disorder and binge drinking

Toronto, Ontario, Oct. 07, 2021 (GLOBE NEWSWIRE) — via InvestorWire — Clearmind Medicine Inc. (CSE: CMND, FSE: CWY0),(“Clearmind” or the “Company“), a psychedelic medicine biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and under treated health problems, today announced that it has engaged Clinipace Incorporated, a full service Contract Research Organization (CRO), to advise the Company in its pursuit of Food and Drug Administration(FDA) approval for its therapeutics.

Clinipace’s first project will be coordinating the submission of a request for an Investigational New Drug (IND) review by the FDA of theCompany’s proprietary MEAI compound for the treatment of alcohol use disorder (AUD) and binge drinking in preparation for Phase I clinical study in humans.

MEAI (5-Methoxy-2-aminoindane) is a novel psychoactive molecule, exerting a euphoric alcohol-like experience and a reduced desire to consume alcoholic beverages. The Company owns six patents covering the use of MEAI for the treatment of AUD and binge behaviour. Pre-clinical study results for MEAI demonstrated a high safety profile and promising efficacy, further supporting the Company’s decision to pursue an IND Review.

Adi Zuloff-Shani, PhD., CEO of Clearmind, commented, “Moving any drug through the FDA approval process requires deep expertise and meticulous attention to detail; this is particularly true for psychedelics. We chose Clinipace as our CRO as they have facilitated dozens of successful regulatory submissions operating at the highest clinical and ethical standards.”

“With this partnership, we are well positioned to advance through the review process in a timely and efficient manner, bringing us closer to establishing MEAI as the basis for changing the way we treat alcohol abuse and other addictive behaviour,” Zuloff-Shani concluded.

About Clearmind Medicine Inc.

Clearmind is a psychedelic pharmaceutical biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and underserved health problems, including alcohol use disorder. Its primary objective is to research and develop psychedelic-based compounds and attempt to commercialize them as regulated medicines, foods or supplements.

The Company’s intellectual portfolio currently consists of two patent families. The first, “Binge Behaviour Regulators,” has been granted in the U.S., Europe, China and India, with pending divisional applications in Europe and the U.S. The second, “Alcohol Beverage Substitute,”has been approved for a European patent, with pending applications in the U.S., China and India. The Company intends to seek additional patents for its compounds whenever warranted and will remain opportunistic regarding the acquisition of additional intellectual property to build its portfolio.

Shares of Clearmind are listed for trading on the Canadian Securities Exchange under the symbol “CMND” and the Frankfurt StockExchange under the symbol “CWY0.”

For further information, please contact:

Investor Relations,
Email: invest@clearmindmedicine.comTelephone: (778) 400-5347
General Inquiries,

Info@Clearmindmedicine.com

www.Clearmindmedicine.com

FORWARD-LOOKING STATEMENTS:

This news release may contain forward-looking statements and information based on current expectations. These statements should not be read as guarantees of future performance or results. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements. Such statements include submission of the relevant documentation within the required timeframe to the satisfaction of the relevant regulators and raising sufficient financing to complete the Company’s business strategy. There is no certainty that any of these events will occur. Although such statements are based on management’s reasonable assumptions, there can be no assurance that such assumptions will prove to be correct. We assume no responsibility to update or revise them to reflect new events or circumstances.

Investing into early-stage companies inherently carries a high degree of risk, and investment into securities of the Company shall be considered highly speculative.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of, the securities in any province in which such offer, solicitation or sale would be unlawful. The securities issued, or to be issued, under the Private Placement have not been, and will not be, registered under the United States Securities Act of 1933, as amended, and may not be offered or sold in theUnited States absent registration or an applicable exemption from registration requirements.

Neither the Canadian Securities Exchange (the “CSE”) nor its Regulation Services Provider (as that term is defined in the policies of theCSE) accepts responsibility for the adequacy or accuracy of this release.

Wire Service Contact

InvestorWire
Los Angeles, California

www.InvestorWire.com

212.418.1217

Editor@InvestorWire.com

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Clearmind Medicine to Host ‘Psychedelics for Alcoholism‘ Virtual Educational Event on October 20

Clearmind Medicine to Host ‘Psychedelics for Alcoholism‘ Virtual Educational Event on October 20

Anexpert panel will present and discuss new potential treatments for Alcohol UseDisorder and binge drinking

TORONTO,Oct. 1, 2021—via InvestorWire – Clearmind Medicine Inc. (CSE:CMND) (“Clearmind” or the “Company“), a psychedelicmedicine biotech company focused on the discovery and development of novelpsychedelic-derived therapeutics to solve widespread and undertreated healthproblems, is pleased to announce it will be hosting Psychedelics ForAlcoholism, a free, live virtual event highlighting new potentialtreatments for alcohol use disorder and binge drinking.

The online event will be held Oct. 20, 2021, starting at 12 p.m.EST/9 a.m. PST; registration is open and free to all. The event will includebrief presentations by featured speakers, followed by a discussion with aquestion-and-answer session.

The Company has curated a panel of scientists, thought leaders,therapists, and pundits to sharetheir experiences and educate participants on the mounting evidence suggestingthe effectiveness of psychedelics, and specifically MEAI, in the regulation ofexcessive drinking .

Representatives from the Company will also provide an updateon Clearmind’s MEAI-based medicines and their potential for the treatment ofAlcohol Use Disorder and binge drinking.

AdiZuloff-Shani, Ph.D., CEO of Clearmind, stated, “We’re in the middle of a PsychedelicRenaissance that is revolutionizing the way we treat mental disorders. We putthis event together to increase awareness of the advances being made in thefield, and more specifically generate awareness of the work Clearmind is doingwith regard to alcohol use and binge drinking.”

“Togetherwith our sponsors and partners, we are eager to share our progress and provideaccess to accurate information to interested communities, including mentalhealth practitioners, researchers, potential patients, investors and thegeneral public,” Zuloff-Shaniconcluded.

Following is a list ofour panelists and partners. To register for the event, or learn more aboutPsychedelics for Alcoholism, visit the event website.

Among our featured speakers and panelists: Shannon Smadella, moderator; Adi Zuloff-Shani, Ph.D., chief executive officer at Clearmind; Mark Haden, Advisory Board member,Clearmind; Terri Freeland, construction industry professional; and Dr. JeffMorley, registered psychologist.

Partners include: Canadian Psychedelic Association, WorldPsychedelics Day, McKennaAcademy of Natural Philosophy™, and Insight Global.

About Clearmind Medicine Inc.

Clearmind (CSE: CMND) is a psychedelicpharmaceutical biotech company focused on the discovery and development ofnovel psychedelic-derived therapeutics to solve widespread and underservedhealth problems, including alcohol use disorder. Its primary objective is toresearch and develop psychedelic-based compounds and attempt to commercializethem as regulated medicines, foods or supplements.

The Company’s intellectual portfoliocurrently consists of two patent families. The first, “Binge BehaviorRegulators,” has been granted in the U.S., Europe, China and India, withpending divisional applications in Europe and the U.S. The second, “AlcoholBeverage Substitute,” has been approved for a European patent, with pendingapplications in the U.S., China and India. The Company intends to seekadditional patents for its compounds whenever warranted and will remainopportunistic regarding the acquisition of additional intellectual property tobuild its portfolio.

Shares of Clearmind are listed fortrading on the Canadian Securities Exchange under the symbol “CMND“and the Frankfurt Stock Exchange under the symbol “CWYO”.

For further information, pleasecontact:

Investor Relations Email:

invest@clearmindmedicine.com

Telephone: (778) 400-5347

General Inquiries Email:

Info@Clearmindmedicine.com

www.Clearmindmedicine.com

FORWARD-LOOKINGSTATEMENTS:

Thisnews release may contain forward-looking statements and information based oncurrent expectations. These statements should not be read as guarantees offuture performance or results. Such statements involve known and unknown risks,uncertainties and other factors that may cause actual results, performance orachievements to be materially different from those implied by such statements.Such statements include submission of the relevant documentation within therequired timeframe to the satisfaction of the relevant regulators and raisingsufficient financing to complete the Company’s business strategy. There is nocertainty that any of these events will occur. Although such statements arebased on management’s reasonable assumptions, there can be no assurance thatsuch assumptions will prove to be correct. We assume no responsibility toupdate or revise them to reflect new events or circumstances.

Investinginto early-stage companies inherently carries a high degree of risk, andinvestment into securities of the Company shall be considered highlyspeculative.

Thispress release shall not constitute an offer to sell or the solicitation of anoffer to buy, nor shall there be any sale of, the securities in any province inwhich such offer, solicitation or sale would be unlawful. The securitiesissued, or to be issued, under the Private Placement have not been, and willnot be, registered under the United States Securities Act of 1933, as amended,and may not be offered or sold in the United States absent registration or anapplicable exemption from registration requirements.

Neitherthe Canadian Securities Exchange (the “CSE”) nor its Regulation ServicesProvider (as that term is defined in the policies of the CSE) acceptsresponsibility for the adequacy or accuracy of this release.

WireService Contact
InvestorWire (IW)
Los Angeles, California
www.InvestorWire.com
212.418.1217 Office
Editor@InvestorWire.com

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Clearmind Medicine To Fund Second R&D Partnership With Hebrew University’s Technology Transfer Company

Clearmind Medicine To Fund Second R&D Partnership With Hebrew University’s Technology Transfer Company

Toronto, Ontario–(Newsfile Corp. – September 27, 2021) – Clearmind Medicine Inc. (CSE: CMND) (“Clearmind” or the “Company“), a psychedelic medicine biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and undertreated health problems, is pleased to announce it has entered an agreement to fund a second research and development project with Yissum Research Development Company (“Yissum”), the technology transfer company of The Hebrew University of Jerusalem.

The project is consistent with the Company’s focus on developing novel therapies that improve mental health, particularly those relating to addiction, binge behavior and depression.

About Yissum Research Development Corporation

Yissum is the technology transfer company of The Hebrew University of Jerusalem. Founded in 1964, it serves as a bridge between cutting-edge academic research and a global community of entrepreneurs, investors, and industry. Yissum’s mission is to benefit society by converting extraordinary innovations and transformational technologies into commercial solutions that address our most urgent global challenges. Yissum has registered over 10,875+ patents globally; licensed over 1140+ technologies and has spun out more than 191 companies. Yissum’s business partners span the globe and include companies such as Boston Scientific, Google, ICL, Intel, Johnson & Johnson, Merck, Microsoft, Novartis and many more. For further information please visit www.yissum.co.il.

About the Hebrew University of Jerusalem

The Hebrew University of Jerusalem is Israel’s first university, formed in 1918 and opened in 1925. Today, there are over 23,000 students enrolled at the University, including undergraduates, master’s degree students, and doctoral candidates. The university has four campuses: Mount Scopus, The Edmond J. Safra (Givat Ram) Campus, and Ein Kerem (in Jerusalem), and Rehovot. Hebrew University Alumni are invited to visit https://new.huji.ac.il.

About Clearmind Medicine Inc.

Clearmind is a psychedelic pharmaceutical biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and underserved health problems, including alcohol use disorder. Its primary objective is to research and develop psychedelic-based compounds and attempt to commercialize them as regulated medicines, foods or supplements.

The Company’s intellectual portfolio currently consists of two patent families. The first, “Binge Behavior Regulators”, has been granted in the U.S., Europe, China and India, with pending divisional applications in Europe and the U.S. The second, “Alcohol Beverage Substitute”, has been approved for a European patent, with pending applications in the U.S., China and India. The Company intends to seek additional patents for its compounds whenever warranted and will remain opportunistic regarding the acquisition of additional intellectual property to build its portfolio.

Shares of Clearmind are listed for trading on the Canadian Securities Exchange under the symbol “CMND” and the Frankfurt Stock Exchange under the symbol “CWYO.”

For further information, please contact:
Investor Relations,
Email: invest@clearmindmedicine.com
Telephone: (778) 400-5347
General Inquiries,
Info@Clearmindmedicine.com
www.Clearmindmedicine.com

FORWARD-LOOKING STATEMENTS:

This news release may contain forward-looking statements and information based on current expectations. These statements should not be read as guarantees of future performance or results. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements. Such statements include submission of the relevant documentation within the required timeframe to the satisfaction of the relevant regulators and raising sufficient financing to complete the Company’s business strategy. There is no certainty that any of these events will occur. Although such statements are based on management’s reasonable assumptions, there can be no assurance that such assumptions will prove to be correct. We assume no responsibility to update or revise them to reflect new events or circumstances.

Investing into early-stage companies inherently carries a high degree of risk, and investment into securities of the Company shall be considered highly speculative.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of the securities in any province in which such offer, solicitation or sale would be unlawful. The securities issued, or to be issued, under the Private Placement have not been, and will not be, registered under the United States Securities Act of 1933, as amended, and may not be offered or sold in the United States absent registration or an applicable exemption from registration requirements.

Neither the Canadian Securities Exchange (the “CSE“) nor its Regulation Services Provider (as that term is defined in the policies of the CSE) accepts responsibility for the adequacy or accuracy of this release.

Not for distribution to U.S. newswire services or dissemination in the United States.

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Clearmind Medicine (CMND) Partners with The Hebrew University to Develop Novel Psychedelic Drug

The R&D project with Yissum Research Development Company will contribute to Clearmind’s IP portfolio

TORONTO, Sept. 21, 2021 (GLOBE NEWSWIRE) — via InvestorWire — Clearmind Medicine Inc. (CSE: CMND) (“Clearmind” or the “Company“), a psychedelic medicine biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and undertreated health problems, is pleased to announce it has established a research and development project with Yissum Research Development Company (“Yissum”), the technology transfer company of The Hebrew University of Jerusalem. The collaboration will focus on developing novel, innovative, patentable psychedelics as potential drug candidates to expand Clearmind’s IP portfolio.

Yissum is known for its ability to discover, analyze and design advanced molecular scaffolds to serve as common platforms for synthesizing various structurally related compounds as potential therapeutic agents and drug candidates.

According to the terms of the agreement, The Hebrew University researchers, professors Dmitry Tsvelikhovsky, Masha Niv and Avi Priel, will work together to investigate and innovate synthetic novel analogs of known psychedelic compounds, conduct in silico 3D docking studies and rational design, and screen the compounds in an in vitro platform.

Adi Zuloff-Shani, Ph.D., CEO of Clearmind, commented on the announcement, “This is an important partnership for Clearmind. The academic/technology transfer model is responsible for many medical breakthroughs, and the Hebrew University-Yissum partnership is one of the most prolific in the field. I am certain that our collaboration will yield many potential candidates for further evaluation.”

“Yissum is looking forward to collaborating with Clearmind in its mission to discover novel psychedelic compounds. We have assigned our top researchers from multiple fields to this project, and I am confident their broad expertise and know-how will facilitate Clearmind’s ability to expand their pipeline portfolio,” said Dr. Ilya Pittel, VP of business development at Yissum Research Development Company.

Professor Tsvelihovsky added, “Professors Avi Priel and Masha Niv and I are excited to work with the team at Clearmind to create unique synthetic compounds for the development of novel GPCR-focused therapeutics. We believe psychedelics are going to revolutionize the treatment of mental health, and Clearmind’s plans put it on the leading edge of innovation in the field. We are quite optimistic that our efforts will lead to new psychotherapy drug candidates.”

About Yissum Research Development Company

Yissum is the technology transfer company of The Hebrew University of Jerusalem. Founded in 1964, it serves as a bridge between cutting-edge academic research and a global community of entrepreneurs, investors and industry. Yissum’s mission is to benefit society by converting extraordinary innovations and transformational technologies into commercial solutions that address our most urgent global challenges. Yissum has registered over 10,875 patents globally, licensed over 1,140 technologies and has spun out more than 191 companies. Yissum’s business partners span the globe and include companies such as Boston Scientific, Google, ICL, Intel, Johnson & Johnson, Merck, Microsoft, Novartis and many more. For further information, please visit www.yissum.co.il.

About the Hebrew University of Jerusalem

The Hebrew University of Jerusalem is Israel’s first university, formed in 1918 and opened in 1925. Today, there are over 23,000 students enrolled at the university, including undergraduates, master’s degree students and doctoral candidates. The university has four campuses: Mount Scopus, The Edmond J. Safra (Givat Ram) Campus, and Ein Kerem, all in Jerusalem, and Robert H. Smith Faculty of Agriculture, Food and the Environment, located in Rehovot. Hebrew University Alumni are invited to visit https://new.huji.ac.il.

About Clearmind Medicine Inc.

Clearmind is a psychedelic pharmaceutical biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and underserved health problems, including alcohol use disorder. Its primary objective is to research and develop psychedelic-based compounds and attempt to commercialize them as regulated medicines, foods or supplements.

The Company’s intellectual portfolio currently consists of two patent families. The first, “Binge Behavior Regulators,” has been granted in the U.S., Europe, China and India, with pending divisional applications in Europe and the U.S. The second, “Alcohol Beverage Substitute,” has been approved for a European patent, with pending applications in the U.S., China and India. The Company intends to seek additional patents for its compounds whenever warranted and will remain opportunistic regarding the acquisition of additional intellectual property to build its portfolio.

Shares of Clearmind are listed for trading on the Canadian Securities Exchange under the symbol “CMND” and the Frankfurt Stock Exchange under the symbol “CWYO.”

For further information, please contact:
Investor Relations,
Email: invest@clearmindmedicine.com
Telephone: (778) 400-5347
General Inquiries,
Info@Clearmindmedicine.com
www.Clearmindmedicine.com

FORWARD-LOOKING STATEMENTS:

This news release may contain forward-looking statements and information based on current expectations. These statements should not be read as guarantees of future performance or results. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements. Such statements include submission of the relevant documentation within the required timeframe to the satisfaction of the relevant regulators and raising sufficient financing to complete the Company’s business strategy. There is no certainty that any of these events will occur. Although such statements are based on management’s reasonable assumptions, there can be no assurance that such assumptions will prove to be correct. We assume no responsibility to update or revise them to reflect new events or circumstances.

Investing into early-stage companies inherently carries a high degree of risk, and investment into securities of the Company shall be considered highly speculative.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of, the securities in any province in which such offer, solicitation or sale would be unlawful. The securities issued, or to be issued, under the Private Placement have not been, and will not be, registered under the United States Securities Act of 1933, as amended, and may not be offered or sold in the United States absent registration or an applicable exemption from registration requirements.

Neither the Canadian Securities Exchange (the “CSE”) nor its Regulation Services Provider (as that term is defined in the policies of the CSE) accepts responsibility for the adequacy or accuracy of this release.

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