Spherix Highlights ValuEngine Upgrade to ‘Buy’ Rating

NEW YORKOct. 17, 2019 /PRNewswire/ — Spherix Incorporated (Nasdaq: SPEX) today announced that its stock has been upgraded to a “buy” rating from a “hold” rating in a research note issued to investors by ValuEngine Inc. (www.valuengine.com). ValuEngine uses proprietary models to forecast and value individual equities across a diverse set of industries.

Spherix Logo. (PRNewsFoto/Spherix Incorporated)

Mr. Anthony Hayes, CEO of Spherix stated, “We continue to work towards building value for our shareholders by opportunistically deploying the Company’s capital across several undervalued assets where we can utilize our industry knowledge and expertise to unlock meaningful returns.”

About Spherix

Spherix Incorporated is a technology development company committed to the fostering of innovative ideas. Spherix Incorporated was formed in 1967 as a scientific research company. Our activities generally include the acquisition and development of technology through internal or external research and development. In addition, we seek to acquire existing rights to intellectual property through the acquisition of already issued patents and pending patent applications, both in the United States and abroad. We may alone, or in conjunction with others, develop products and processes associated with technology development and monetizing related intellectual property.

Forward-Looking Statements

Certain statements in this press release constitute “forward-looking statements” within the meaning of the federal securities laws. Words such as “may,” “might,” “will,” “should,” “believe,” “expect,” “anticipate,” “estimate,” “continue,” “predict,” “forecast,” “project,” “plan,” “intend” or similar expressions, or statements regarding intent, belief, or current expectations, are forward-looking statements. While the Company believes these forward-looking statements are reasonable, undue reliance should not be placed on any such forward-looking statements, which are based on information available to us on the date of this release. These forward looking statements are based upon current estimates and assumptions and are subject to various risks and uncertainties, including without limitation those set forth in the Company’s filings with the SEC, not limited to Risk Factors relating to its patent business contained therein. Thus, actual results could be materially different. The Company expressly disclaims any obligation to update or alter statements whether as a result of new information, future events or otherwise, except as required by law.

Contact:

Investor Relations:

Hayden IR                              

Brett Maas, Managing Partner

Phone: (646) 536-7331

Email: brett@haydenir.com  

www.haydenir.com

Spherix:

Phone: 212-745-1373                         

Email: investorrelations@spherix.com

www.spherix.com

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Vireo Health Launches 1937 Cannabis Brand

1937 Cannabis features historic cannabis strains and will be available in both dry flower and concentrates

MINNEAPOLIS, Oct. 17, 2019 /PRNewswire/ — Vireo Health International, Inc. (“Vireo” or the “Company”) (CNSX: VREO; OTCQX: VREOF), a leading physician-founded, science-focused multi-state cannabis company, today announced the launch of 1937 Cannabis, a new brand of professional grade cannabis-based products. 1937 Cannabis represents the Company’s first launch of a new cannabis brand and first time offering dry flower. The 1937 Cannabis product line features dry flower and will expand to include concentrates later this year.

Vireo's new brand, 1937 Cannabis, will feature dry flower and concentrates in legendary strains. Pictured is the first release of dry flower in Pennsylvania.

1937 Cannabis (www.1937cannabis.com) is now available in dispensaries throughout Pennsylvania and Maryland and features legendary strains such as ‘Bubba Kush’ and ‘Sweet Cheese’ that are handpicked and hand-packaged to assure only the best flower is utilized. The flower is cured for extended time periods to create a smoother taste, enhanced terpene profile, and deeper aromatics. 1937 Cannabis is 100% pesticide free and sold in premium, airtight glass jars.

“We are excited to announce the launch of 1937, a new line of premium-quality cannabis products,” said CEO and Founder Kyle Kingsley, MD. “By expanding our product lines to include dry flower, we are increasing access and affordability, while providing our customers – both cannabis connoisseurs and medical patients alike – with new choices and opportunities to discover which products best meet their individual needs.”

“Vireo is developing a strong portfolio of brands that engage and delight both recreation and medical consumers,” added Harris Rabin Chief Marketing Officer of Vireo Health. “1937 is our second major brand, but we are creating and launching a variety of exciting, new brands for every occasion our customers have to enjoy cannabis products.”

The brand name, 1937, is a reference to The Marihuana Tax Act of 1937, federal legislation designed to prohibit cannabis use. As Americans across the country work to end cannabis prohibition, the 1937 brand proudly stands for social justice and equality for all.

The Company plans to expand the 1937 Cannabis product line in Pennsylvania and Maryland and to make it available in other state-based markets in which Vireo is licensed to operate.

Learn more at: www.1937cannabis.com/ or follow the brand on Instagram www.instagram.com/1937cannabis/.

About Vireo Health International, Inc.
Vireo Health International, Inc.’s mission is to build the cannabis company of the future by bringing the best of medicine, engineering and science to the cannabis industry. Vireo’s physician-led team of nearly 400 employees provides best-in-class cannabis products and customer experience. Vireo cultivates cannabis in environmentally friendly greenhouses, manufactures pharmaceutical-grade cannabis extracts, and sells its products at both company-owned and third-party dispensaries. The Company currently is licensed in eleven markets including Arizona, Maryland, Massachusetts, Minnesota, New Mexico, New York, Nevada, Ohio, Pennsylvania, Puerto Rico, and Rhode Island. For more information about the Company, please visit www.vireohealth.com.

Contact Information

Media Inquiries
Albe Zakes
Vice President, Corporate Communications
albezakes@vireohealth.com
(267) 221-4800

Investor Inquiries
Sam Gibbons
Vice President, Investor Relations
samgibbons@vireohealth.com
(612) 314-8995

Vireo Health Names Ari Hoffnung Chief Strategy Officer

MINNEAPOLIS, Oct. 14, 2019 /PRNewswire/ — Vireo Health International, Inc. (“Vireo” or the “Company”) (CNSX: VREO; OTCQX: VREOF), a leading physician-founded, science-focused multi-state cannabis company, today announced the promotion of Chief Operating Officer ­Ari Hoffnung to the newly created role of Chief Strategy Officer. Mr. Hoffnung also serves on Vireo’s Board of Directors.

Vireo Logo (PRNewsfoto/Vireo Health, Inc.)

As Chief Strategy Officer, Mr. Hoffnung will continue to report to Chief Executive Officer Kyle Kingsley, M.D. and lead the Company’s corporate communications, government affairs, and public policy efforts, both locally in state-based markets throughout the country and federally in Washington, D.C. He will also continue to manage the Vireo’s growing eCommerce and Home Delivery sales channels along with the Information Technology and Security teams.

“Since joining in 2015, Ari has had a huge positive impact on Vireo’s growth and success. As Chief Operating Officer, Ari’s broad skill sets and leadership abilities helped us transform our business from a one-state operator into the impressive multi-state operator we are today,” said Chief Executive Officer Kyle Kingsley, M.D. “I am confident that in his new role, Ari will continue to successfully guide our company through the rapidly evolving legislative and business landscapes.”

Mr. Hoffnung joined Vireo in 2015 as the Chief Executive Officer of Vireo Health of New York and brings more than two decades of leadership experience on Wall Street, New York City Hall and the cannabis industry to the position of Chief Strategy Officer. He was previously the founder and CEO of Fiorello Pharmaceuticals, Inc., a New York-based medical cannabis company. Prior to that, Mr. Hoffnung served as New York City’s Deputy Comptroller for Budget & Public Affairs, where he oversaw the City’s $70 billion budget. Prior to serving in New York City government, Mr. Hoffnung was a Managing Director at Bear Stearns, where he worked for more than a decade. He holds a Master of Business Administration in Finance degree from New York University’s Stern School of Business and a Bachelor’s degree from Queens College.

The Company also announced that promotions of Christian Gonzales to Executive Vice President of Operations, overseeing Vireo’s manufacturing and retail operations, and Gary Starr, M.D to Deputy Chief Executive Officer of Minnesota Medical Solutions (MinnMed), the company’s wholly owned subsidiary in the State of Minnesota.

About Vireo Health International, Inc.
Vireo Health International, Inc.’s mission is to build the cannabis company of the future by bringing the best of medicine, engineering and science to the cannabis industry. Vireo’s physician-led team of nearly 400 employees provides best-in-class cannabis products and customer experience. Vireo cultivates cannabis in environmentally friendly greenhouses, manufactures pharmaceutical-grade cannabis extracts, and sells its products at both company-owned and third-party dispensaries. The Company currently is licensed in eleven markets including Arizona, Maryland, Massachusetts, Minnesota, New Mexico, New York, Nevada, Ohio, Pennsylvania, Puerto Rico, and Rhode Island. For more information about the Company, please visit www.vireohealth.com.

Contact Information

Media Inquiries
Albe Zakes
Vice President, Corporate Communications
albezakes@vireohealth.com
(267) 221-4800

Investor Inquiries
Sam Gibbons
Vice President, Investor Relations
samgibbons@vireohealth.com
(612) 314-8995

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Spherix Sets Record Date for Dividend Distribution

NEW YORKOct. 11, 2019 /PRNewswire/ — Spherix Incorporated (Nasdaq: SPEX) today announced that on October 2, 2019, the Board of Directors of Spherix Incorporated (“Spherix”) approved a distribution to Spherix stockholders of 100,000 shares of Hoth Therapeutics, Inc. (“Hoth”) held by Spherix.

Spherix Logo. (PRNewsFoto/Spherix Incorporated)

Each Spherix stockholder will be entitled to receive one (1) share of Hoth common stock for every twenty-nine (29) shares of Spherix common stock held as of 5 p.m. Eastern Time on October 21, 2019, the record date. Spherix will not distribute fractional shares of Hoth common stock, and any fractional shares will be rounded down to the nearest whole share.

Spherix stockholders do not need to take any action to receive the shares of Hoth common stock, other than be a shareholder of record on October 21, 2019. Spherix stockholders do not need to pay any consideration for, surrender or exchange shares of Spherix common stock.

Mr. Anthony Hayes, CEO of Spherix stated, “Returning capital to shareholders is an important part of our strategy, and the distribution of a portion of our holdings in Hoth is the first step in this endeavor. We continue to work towards becoming a diversified biopharmaceutical company with a compelling portfolio of potential compounds to develop and commercialize.”

About Spherix

Spherix Incorporated is a technology development company committed to the fostering of innovative ideas. Spherix Incorporated was formed in 1967 as a scientific research company.
Our activities generally include the acquisition and development of technology through internal or external research and development. In addition, we seek to acquire existing rights to intellectual property through the acquisition of already issued patents and pending patent applications, both in the United States and abroad. We may alone, or in conjunction with others, develop products and processes associated with technology development. Recently, the Company has invested in and helped develop technology with Hoth Therapeutics, Inc., DatChat, Inc. and entered into an agreement to acquire certain technology assets from CBM BioPharma, Inc.

Forward-Looking Statements

Certain statements made herein are not historical facts but are forward-looking statements for purposes of the safe harbor provisions under The Private Securities Litigation Reform Act of 1995. Forward-looking statements generally are accompanied by words such as “may”, “should”, “would”, “plan”, “intend”, “anticipate”, “believe”, “estimate”, “predict”, “potential”, “seem”, “seek”, “continue”, “future”, “will”, “expect”, “outlook” or other similar words, phrases or expressions. These forward-looking statements include statements regarding Spherix’s and CBM’s industry, future events, the proposed transaction between the parties to the Asset Purchase Agreement, the estimated or anticipated future results and benefits of the Company following the transaction, including the likelihood and ability of the parties to successfully consummate the proposed transaction, future opportunities for the combined company, and other statements that are not historical facts. These statements are based on the current expectations of Spherix’s management and are not predictions of actual performance. These statements are subject to a number of risks and uncertainties regarding the businesses of Spherix and the transaction, and actual results may differ materially. These risks and uncertainties include, but are not limited to, changes in the business environment in which Spherix or CBM operates, including inflation and interest rates, and general financial, economic, regulatory and political conditions affecting the industry in which Spherix or CBM operates; changes in taxes, governmental laws, and regulations; competitive product and pricing activity; difficulties of managing growth profitably; the inability of the parties to successfully or timely consummate the proposed transaction, including the risk that any required regulatory approvals are not obtained, are delayed or are subject to unanticipated conditions that could adversely affect the combined company or the expected benefits of the transaction; failure to realize the anticipated benefits of the transaction, including as a result of a delay in consummating the transaction or a delay or difficulty in integrating the assets of CBM; uncertainty as to the long-term value of Spherix’s common stock; those discussed in the Spherix’s Annual Reports on Form 10-K and Quarterly Reports on Form 10-Q and other documents of Spherix on file with the SEC or in the registration statement that will be filed with the SEC by Spherix. There may be additional risks that Spherix presently does not know or that Spherix currently believes are immaterial that could also cause actual results to differ from those contained in the forward-looking statements. In addition, forward-looking statements provide Spherix’s expectations, plans or forecasts of future events and views as of the date of this communication. Spherix anticipates that subsequent events and developments will cause Spherix’s assessments to change. However, while Spherix may elect to update these forward- looking statements at some point in the future, Spherix specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing Spherix’s assessments as of any date subsequent to the date of this communication.

Contact:

Investor Relations:

Hayden IR

Brett Maas, Managing Partner

Phone: (646) 536-7331

Email: brett@haydenir.com

www.haydenir.com

Spherix:

Phone: 212-745-1373

Email: investorrelations@spherix.com

www.spherix.com

 

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Vireo Health Employees Ratify First Cannabis Union Contract in Pennsylvania with UFCW 1776KS

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Vireo Health to Present at the Canaccord Genuity U.S. Cannabis Symposium

MINNEAPOLIS, Oct. 2, 2019 /PRNewswire/ — Vireo Health International, Inc. (“Vireo” or the “Company”) (CNSX: VREO; OTCQX: VREOF), a leading physician-led, science-focused, multi-state cannabis company, today announced its participation at the Canaccord Genuity U.S. Cannabis Symposium in Toronto on October 3, 2019.

Vireo Logo (PRNewsfoto/Vireo Health, Inc.)

Chief Executive Officer Kyle Kingsley, M.D., will present and meet with investors at the conference. Dr. Kingsley’s presentation will begin at approximately 12:50 p.m. ET (11:50 a.m. CT). An electronic copy of Dr. Kingsley’s presentation will be available in the investor relations section of Vireo’s website.

The Canaccord Genuity U.S. Cannabis Symposium is a one-day event featuring company presentations and one-on-one meetings with senior management teams representing every facet of the U.S. cannabis industry, including multi-state operators, technology providers, brand owners, hemp producers, oil extractors and ancillary products businesses. Investors interested in meeting with Vireo management at this event should contact their Canaccord representative.

About Vireo Health International, Inc.

Vireo Health International, Inc.’s mission is to build the cannabis company of the future by bringing the best of medicine, engineering and science to the cannabis industry.  Vireo’s physician-led team of nearly 400 employees provides best-in-class cannabis products and customer experience. Vireo cultivates cannabis in environmentally friendly greenhouses, manufactures pharmaceutical-grade cannabis extracts, and sells its products at both company-owned and third-party dispensaries. The Company currently is licensed in eleven markets including Arizona, Maryland, Massachusetts, Minnesota, New Mexico, New York, Nevada, Ohio, Pennsylvania, Puerto Rico, and Rhode Island.  For more information about the Company, please visit www.vireohealth.com.

Contact Information 

Investor Inquiries
Sam Gibbons
Vice President, Investor Relations
samgibbons@vireohealth.com
(612) 314-8995

Media Inquiries
Albe Zakes
Vice President, Corporate Communications
albezakes@vireohealth.com
(267) 221-4800

 

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SOURCE Vireo Health International, Inc.

Spherix Issues Update to Shareholders

NEW YORKOct. 1, 2019 /PRNewswire/ — Spherix Incorporated (Nasdaq: SPEX) President and CEO, Anthony Hayes, today released a letter to shareholders.

Spherix Logo. (PRNewsFoto/Spherix Incorporated)

Dear Fellow Shareholders,

As previously stated, Spherix is moving forward diligently with the dividend distribution.  Spherix shareholders who are owners of record on the record date to be set by the Spherix board of directors, will be paid the dividend.  That process is on track and moving forward.  We intend to announce a record date shortly.

In addition, I wanted to provide some additional information about the CBM assets that are part of the planned acquisition.  Like other AML drugs that treat certain indications, KPC34 may qualify for Fast Track designation for the treatment of certain types of AML, as well as priority review by the FDA.  Developed at Wake Forest School of Medicine, KPC34 is a proprietary next generation drug that combines a DNA damaging agent with a targeted therapy designed to overcome multiple resistance mechanisms observed with gemcitabine, the current standard of care. KPC34 has also been shown to be more effective in AML relapse cases, notably increasing the lifespan of mice treated with the drug. The competitive benefits of KPC34 include oral application for patients that cannot tolerate repeated cycles of chemotherapy, doubling the mean survival time verse some of the current standard of care treatments and studies further show high activity levels against human AML cells.

Upon the closing of the CBM asset purchase, and following the dividend distribution, we will further update the market on the CBM assets and the status of our other strategic acquisitions.  We understand the desire by shareholders to receive the proposed dividend and information about Company activities during a tumultuous market.  We hope this release provides additional information and assure you we are working diligently to move matters forward.

Thank you for being a shareholder of Spherix.

Sincerely,

Anthony Hayes

About Spherix
Spherix Incorporated was launched in 1967 as a scientific research company. Spherix is committed to advancing innovation by active participation in the patent market. Spherix draws on portfolios of pioneering technology patents to partner with and support product innovation.

Forward-Looking Statements
Certain statements in this press release constitute “forward-looking statements” within the meaning of the federal securities laws. Words such as “may,” “might,” “will,” “should,” “believe,” “expect,” “anticipate,” “estimate,” “continue,” “predict,” “forecast,” “project,” “plan,” “intend” or similar expressions, or statements regarding intent, belief, or current expectations, are forward-looking statements. While the Company believes these forward-looking statements are reasonable, undue reliance should not be placed on any such forward-looking statements, which are based on information available to us on the date of this release. These forward looking statements are based upon current estimates and assumptions and are subject to various risks and uncertainties, including without limitation those set forth in the Company’s filings with the Securities and Exchange Commission (the “SEC”), not limited to Risk Factors relating to its patent business contained therein. Thus, actual results could be materially different. The Company expressly disclaims any obligation to update or alter statements whether as a result of new information, future events or otherwise, except as required by law.

Contact:

Investor Relations: 

Hayden IR

Brett Mass, Managing Partner

Phone: (646) 536-7731

Email: brett@haydenir.com

www.haydenir.com

Spherix:

Phone: 212-745-1373

Email: investorrelations@sherix.com

www.spherix.com

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Spherix Issues Update to Shareholders Regarding Planned Dividend Distribution

NEW YORKSept. 25, 2019 /PRNewswire/ — Spherix Incorporated (Nasdaq: SPEX) President and CEO, Anthony Hayes, today released a letter to shareholders outlining the Company’s plans for its previously disclosed dividend distribution.

Spherix Logo. (PRNewsFoto/Spherix Incorporated)

Dear Fellow Shareholders,

I want to thank all of you who recently voted to approve the Company’s purchase of CBM BioPharma, Inc.’s assets. As previously stated, Spherix is moving forward with the distribution of 100,000 shares of common stock of Hoth Therapeutics, Inc. to its shareholders.

Spherix’s Board of Directors will meet to set a record date for the stock dividend. Our shareholders who are owners of record on the record date will be paid the dividend distribution.  Shareholders who are not registered as of this date will not receive the dividend distribution.  Spherix’s Board of Directors will also establish the ratio, which will designate how many shares of Hoth common stock each shareholder will receive for every share of Spherix stock owned by such shareholder.  Once this amount is set, Spherix will publicly announce this information, including the record date, and we will instruct Hoth’s transfer agent to distribute the dividend distribution to the Spherix shareholders of record.

We understand the desire to receive the dividend and are working diligently to effectuate the dividend distribution. However, since we are issuing securities in another company, as opposed to cash, it is naturally a slower process. I want to assure each of our shareholders that we are working diligently on this matter and are moving as expeditiously as practicable to complete the dividend distribution.

Spherix continues to pursue additional strategic acquisitions to enhance shareholder value. Our recent press releases on the options we acquired from the University of Kentucky and the University of Maryland, Baltimore present exciting opportunities for the Company. Upon the closing of the CBM asset purchase, and following the dividend distribution, we will further update the market on the status of our other strategic acquisitions.

Thank you for being a shareholder of Spherix.

Sincerely,

Anthony Hayes

About Spherix
Spherix Incorporated was launched in 1967 as a scientific research company. Spherix is committed to advancing innovation by active participation in the patent market. Spherix draws on portfolios of pioneering technology patents to partner with and support product innovation.

Forward-Looking Statements
Certain statements in this press release constitute “forward-looking statements” within the meaning of the federal securities laws. Words such as “may,” “might,” “will,” “should,” “believe,” “expect,” “anticipate,” “estimate,” “continue,” “predict,” “forecast,” “project,” “plan,” “intend” or similar expressions, or statements regarding intent, belief, or current expectations, are forward-looking statements. While the Company believes these forward-looking statements are reasonable, undue reliance should not be placed on any such forward-looking statements, which are based on information available to us on the date of this release. These forward looking statements are based upon current estimates and assumptions and are subject to various risks and uncertainties, including without limitation those set forth in the Company’s filings with the Securities and Exchange Commission (the “SEC”), not limited to Risk Factors relating to its patent business contained therein. Thus, actual results could be materially different. The Company expressly disclaims any obligation to update or alter statements whether as a result of new information, future events or otherwise, except as required by law.

Contact:

Investor Relations:

Hayden IR

Brett Mass, Managing Partner

Phone: (646) 536-7331

Email: brett@haydenir.com

www.haydenir.com

Spherix:

Phone: 212-745-1373

Email: investorrelations@spherix.com

www.spherix.com

 

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SOURCE Spherix Incorporated

VENCLEXTA®, a treatment for chronic lymphocytic leukemia (CLL), now reimbursed across Western Canada

Montreal, QC, September 25, 2019 – AbbVie (NYSE: ABBV), a global research and development-based biopharmaceutical company, announced today that Alberta, Manitoba, British Columbia and Saskatchewan are listing VENCLEXTA® (venetoclax) on their public formularies. VENCLEXTA monotherapy is indicated for the treatment of patients with chronic lymphocytic leukemia (CLL) who have received at least one prior therapy and for whom there are no other available treatment options. VENCLEXTA is an oral, once-daily medicine.

 

“People living with chronic lymphocytic leukemia in Western Canada finally have access to Venclexta, which is great news considering the nature of this disease. When faced with CLL, which can be recurrent, it is important to offer physicians and their patients highly effective options to tackle this illness,” explains Elizabeth Lye, Director of Research & Programs at Lymphoma Canada. “At Lymphoma Canada, we hope that soon all Canadians will have access to this treatment.”

 

VENCLEXTA is listed under the Alberta Health Services, Outpatient Cancer Drug Benefit Programi, as a Part 3 benefit in Manitoba Pharmacare’s Home Oncology Drug Programii, by the British Columbia Cancer Lymphoma Tumour Groupiii and on the formulary of the Saskatchewan Cancer Agencyiv. All four provinces reimburse VENCLEXTA monotherapy for CLL patients who have received at least one prior therapy and who have failed a B-Cell receptor inhibitor (BCRi), with specific criteria.

 

For further information regarding specific provincial criteria consult the links below:

 

“As a clinician, I need to have several treatment options available for my patients to effectively and successfully treat their CLL. It is great news that venetoclax is now reimbursed for Western Canadians,” says Dr. Carolyn Owen, MD, MDres(UK), FRCPC, Associate Professor, Division of Hematology and Hematological Malignancies, Foothills Medical Centre. “Venetoclax is an innovative molecule that selectively inhibits the BCL-2 protein, which is responsible for helping cancer cells survive in the blood.”

 

CLL, which is typically a slow-progressing cancer of the bone marrow and bloodv, is one of the most common types of leukemia in adults. In Canada, CLL accounts for approximately 1,745 newly diagnosed cases of leukemia each year and is responsible for more than 600 deaths a year.vi

 

“When my physician told me I had CLL, I had no idea what this meant for my life expectancy. I am a husband, father and grandfather and I want to be around for my family as long as possible,” explains

 

Dale Jordan of Calgary, Alberta. “After discussing my options with my physician, he recommended VENCLEXTA. I am fortunate to live in a province where people can now access this medication.”

 

VENCLEXTA is being developed by AbbVie and Genentech, a member of the Roche Group. It is jointly commercialized by the companies in the U.S. and by AbbVie outside of the U.S.

 

About AbbVie Care

Canadians prescribed VENCLEXTA will have the opportunity to be enrolled in AbbVie Care, AbbVie’s signature care program. The program is designed to provide a wide range of customized services including reimbursement and financial support, pharmacy services, lab work reminders and coordination, personalized education and ongoing disease management support throughout the treatment. For more information, please visit www.abbviecare.ca.

 

About AbbVie

AbbVie is a global, research and development-driven biopharmaceutical company committed to developing innovative advanced therapies for some of the world’s most complex and critical conditions. The company’s mission is to use its expertise, dedicated people and unique approach to innovation to markedly improve treatments across four primary therapeutic areas: immunology, oncology, virology and neuroscience. In more than 75 countries, AbbVie employees are working every day to advance health solutions for people around the world. For more information about AbbVie, please visit us at www.abbvie.ca and www.abbvie.com. Follow @abbvieCanada and @abbvie on Twitter or view careers on our Facebook or LinkedIn page.

 

 

-30-

Media Inquiries:

Muriel Haraoui muriel.haraoui@abbvie.com 514.717.3764

 

i Alberta Health Services. https://www.albertahealthservices.ca/assets/programs/ps-1025651-drug-benefit-list.pdf. Accessed September 2019.

ii Manitoba Pharmacare. Manitoba Drug Benefits and Interchangeability Formulary Amendments. Bulletin #105. Effective August 22, 2019. https://www.gov.mb.ca/health/mdbif/docs/bulletins/bulletin105.pdf. Accessed

September 2019.

iii BC Cancer. Provincial Systemic Therapy Program. September 2019. http://www.bccancer.bc.ca/systemic- therapy-site/Documents/2019%20ST%20Updates/ST%20Update_Sep%202019.pdf. Accessed September 2019. iv Saskatchewan Cancer Agency Drug Formulary. September 3, 2019. http://www.saskcancer.ca/Drug%20Formulary%2009-2013. Accessed September 2019.

v Lymphoma Canada. Chronic lymphocytic leukemia. Available at www.lymphoma.ca/lymphoma/lymphoma- 101/types-lymphoma/cll. Accessed September 2019.

vi Canadian Cancer Statistics. Chronic lymphocytic leukemia statistics. www.cancer.ca/en/cancer- information/cancer-type/leukemia-chronic-lymphocytic-cll/statistics/?region=on. Accessed September 2019.

GABA Therapeutics and ATAI Life Sciences Partner to Develop a Novel GABA Modulator for the Treatment of Mood Disorders

NEWPORT BEACH, Calif. and BERLIN, Sept. 20, 2019 /PRNewswire/ — Today, GABA Therapeutics, a biotech company focused on the treatment of mood disorders, and ATAI Life Sciences, a global biotech company builder working on paradigm shifting interventions for unmet needs in the mental health space, announced a partnership to develop a novel compound that promises efficacy across a spectrum of mood disorders, particularly anxiety and depression.

GABA Therapeutics’ lead compound, GRX-917, is a deuterated version of etifoxine, a safe and effective anxiolytic medication approved in approximately 40 countries with rapid onset and efficacy comparable to leading benzodiazepines like alprazolam (Xanax™) and lorazepam (Ativan™). In contrast to these and other benzodiazepines, however, more than 30 years of clinical experience with etifoxine suggest that GRX-917 is unlikely to produce serious side effects like sedation, amnesia, tolerance or physical dependence.

“GABA’s work with GRX-917 is critical for addressing the needs of millions of people living with treatment resistant mental illnesses,” said Florian Brand, CEO & Co-Founder, ATAI Life Sciences. “By providing a safe way to meaningfully alleviate anxiety, not only will we improve peoples’ quality of life, we’ll also help them to better engage with their care providers.”

Notably, etifoxine is thought to achieve its anxiolytic activity by increasing central levels of neurosteroids, endogenous compounds (e.g. allopregnanolone) with potent antidepressant, neuroprotective, neurotrophic and anti-inflammatory properties, thereby affording GRX-917 the potential to treat a broad range of CNS diseases. With an improved pharmacokinetic profile that enables less frequent and lower dosing regimens, GRX-917 represents a leap forward for patients seeking to manage their anxiety acutely, safely and reliably.

The Series A investment of up to $15.5 million will fund the program through a Phase 2a proof-of-concept study.

“We are very pleased to partner with the team at ATAI,” said Dr. Ian J. Massey, CEO, GABA. “They are building a world-class portfolio of mental health companies and GRX-917’s potential to address the immense unmet medical need of unmanaged anxiety makes it a natural addition. We are grateful to have the funding and support of ATAI to drive forward this important program.”

“We are thrilled to partner with GABA and will fully support all efforts to bring GRX-917 to patients as quickly as possible,” added Christian Angermayer, Founder, ATAI Life Sciences.

About ATAI Life Sciences

ATAI Life Sciences AG is a global biotech platform and company builder founded by Christian Angermayer. Based in Berlin, London and New York, its vision is to cure mental health disorders, enabling people to live healthier and happier lives. www.atai.life

About GABA Therapeutics

GABA Therapeutics is a California based biotechnology company focused on developing its lead compound GRX-917 for anxiety, depression and a broad range of neurological disorders. GRX-917 has the potential to become front-line therapy for anxiety and has composition-of-matter patent protection until 2036. Moreover, preclinical studies using etifoxine have demonstrated efficacy in a broad range of other neurological disorders, including pain, multiple sclerosis, epilepsy and Alzheimer’s disease.

For more detailed information on GABA Therapeutics, visit www.gabarx.com.

About Anxiety

Anxiety, which is frequently comorbid with depression, is the largest mental health issue in North America. It is estimated that one third of the North American adult population experiences anxiety issues, yet only one third of sufferers receive treatment, of whom only 10% experience any form of remission. This is largely due to limitations in current therapies. In 2018, there were approximately 140 million prescriptions of anxiety medications in the United States(2).

(1)  anxietycentre.com
(2)  IQVIA market data – 2018

Contact
Richard G Farrell
Chief Financial Officer
rfarrell@gabarx.com

Allan Malievsky
Communications Associate
Allan@ATAI.life

SOURCE ATAI Life Sciences

Related Links

https://www.atai.life