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Predict which psychedelics are right for you

Entheon Biomedical Announces Expanded Psychedelics Genetic Test Panel & New Clinical Research Platform

Ketamine therapy for depression seems promising, but how do you know if it’s right for you?

About 30% of people have a genetic variant that impairs the secretion of BDNF, a protein that promotes the growth of neurons.

Since ketamine works by increasing the release of BDNF, people with this gene variant may have a decreased response to the antidepressant effects of ketamine therapy.

HaluGen just expanded its Psychedelics Genetic Test Kit to test for the gene variant! It also tells you how sensitive you’re to classical psychedelics and if you are at risk for schizophrenia, bipolar disorder, or psychosis.

Use code “DAILYMUSHROOM” to get 10% off HaluGen’s Psychedelics Genetic Test!

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Why the UK is becoming a psychedelic hotspot

Brexit Britain becomes unlikely psychedelic haven as Albert Labs IPOs

The UK is on a mission to create a world-leading clinical research ecosystem that’s more efficient and effective than ever before – and many psychedelic companies are taking advantage of the regulatory changes.

To reach this goal, the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) now allows “real world data” (data collected from patients and healthcare systems outside of clinical trials) to aid in the drug approval process

This may bring psychedelic therapies to market much faster not only in the UK, but also in Australia, Canada, Singapore and Switzerland, as the MHRA joined a coalition with these countries called the Access Consortium.

Additionally, the UK may reschedule psilocybin to Schedule 2, reducing barriers to clinical research.

Just yesterday, COMPASS Pathways (CMPS) announced a strategic partnership to launch a major psychedelic research center in the UK.

Other companies to keep an eye on that may benefit from these changes include Albert Labs (ABRT), Awakn Life Sciences (AWKN), Small Pharma (DMT), Beckley Psytech, Eleusis.

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A push for equity + global rescheduling of psilocybin

Global Wellness Institute Announces New Initiative on Psychedelics & Healing

Major non-profit Global Wellness Institute just launched a Psychedelics & Healing Initiative with the goal of establishing evidence-based best practices, equity, and accessibility within the psychedelics industry.

The initiative brings together physicians, business innovators, research scientists, impact investors, and policy makers, including high-profile members like Rick Doblin, founder of MAPS.

The group will also advocate for the International Therapeutic Psilocybin Rescheduling Initiative, a recent movement to suspend psilocybin’s Schedule I status through the United Nations to remove research barriers across the globe.

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The shift toward nature-based psychedelic therapy 🌲

The potential synergistic effects between psychedelic administration and nature contact for the improvement of mental health

Experts from Imperial College London predict that combining psychedelics and contact with nature could have a beneficial synergy, as both are known to decrease rumination, increase mindfulness, and elicit feelings of awe and transcendence.

Combining the two could also restore the disconnect and fear of nature that more and more people are feeling as technology takes over.

In their review, the researchers note that it may be beneficial to incorporate natural elements into treatment rooms and include contact with nature in the therapy sessions leading up to and following the psychedelic session.

While a fully outdoor session has drawbacks, the researchers explain that a hybrid indoor/outdoor with large skylights and windows and nature-based design elements would be the ideal setting for psychedelic therapy.

Organizations like Usona Institute and Synthesis Institute are already working to incorporate nature into treatment programs – let’s hope this trend continues!

SAGE Journals

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Finally, a fun and easy way to lose weight 🍄

NeonMind Reports Business Highlights on Partnership Activities, Clinical Pipeline and Corporate Developments

Almost 40% of adults are overweight and obesity rates have tripled since the 70s. Luckily, both micro and macro doses of psilocybin may be able to combat this.

How? Psilocybin is structurally similar to serotonin, which is known to suppress the appetite.

NeonMind (NEON) found that when rats had unlimited access to food, those on both high and low doses of psilocybin gained 30% less weight than a control group.

The company is preparing for a clinical trial to see if a high dose of psilocybin combined with behavioral therapy and lifestyle intervention can aid in weight management. NeonMind is also developing a psilocybin microdose to control hunger.

Learn more about psychedelics and microdosing with Chloe Deutscher on TikTok!

@chloegoesinward

Check out @dailymushroom.co for more 🍄 news! #psychedelictok #mushroom #microdoselife #psychedelicresearch #psychedelicjourney #psychonaut #plantmedicine

♬ Paper Birds (3 min) – Jordan Halpern Schwartz

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Are psychedelics the key to a healthy family dynamic?

‘I Did Ayahuasca With My Parents And It Deepened Our Relationship’

To learn more about psychedelic medicine, Dr. Adele Lafrance attended an ayahuasca ceremony with her parents. It was so transformative that she’s planning to conduct studies on how psychedelics can support healthy family relationships.

She explains that the ceremony “planted the seeds for deeper emotional intimacy” and allowed her family to talk about love in a vulnerable way for the first time. The experience helped her heal from painful childhood memories.

“I felt a level of understanding toward my parents that was so deep, forgiveness wasn’t necessary. It was beautiful.”

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Octopuses are antisocial creatures, unless they’re on molly 🐙

5 Questions for Gul Dolen

When given MDMA, octopuses spent much more time on the social side of the tank with another octopus. They also showed playful behaviour like floating around as if they were dancing and even doing backflips. 

MDMA is believed to work by targeting part of the brain like the amygdala, prefrontal cortex, nucleus accumbens, and the default mode network. What’s interesting is that octopuses seemed to respond to the drug similarly as humans even though they don’t have these brain structures 🤔

This is why it needs to be easier to research these drugs – there’s still so much we don’t know!

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Replace alcohol with this legal psychedelic drink

Psychedelic Water is a mildly psychoactive drink made with kava root, a herb used by Pacific Islanders in ceremonies for relaxation. The mood-boosting effect makes it the ideal replacement for alcohol. 

Psychedelic Water is having a buy one get one free sale to celebrate the launch of a new flavour – Prickly Pear!

Even multi-platinum producer Murda Beatz is a fan. “I want something that will make me feel good & expand my creativity; Psychedelic Water does exactly that,” he says.

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Acid-inspired invention earns Nobel Prize

The Nobel Prize-Winning, LSD Dropping, Yet Problematic Scientist Who Invented PCR

LSD led to the invention of a technology that has slowed the spread of Covid and even earned a Nobel Prize – the PCR test.

Chemist Kary Mullis experimented with lots of synthetic psychedelics, which is no surprise considering he was friends with Albert Hofmann, the creator of LSD. 

He believes psychedelics made him think more creatively and gave him visions of sitting on DNA molecules. When asked if he would have invented PCR technology without LSD, he responded, “I doubt it. I seriously doubt it.”

So this pandemic would likely be a lot longer if it weren’t for LSD!

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