Posted on

A sweet way to make psilocybin

Danish Synthetic Biology Drug Developer Octarine and British Clinical Research Organisation Clerkenwell Health Partner to Bring Innovative Psychedelics to Patients

This Copenhagen-based company is making psilocybin out of sugar!

Octarine Bio developed an innovative process of producing psilocybin from sugar using yeast fermentation. Not only is the process IP-protected, but its also low cost, sustainable, easily scalable, and has a stable supply chain.

This week, Octarine Bio partnered with a British clinical research organization, Clerkenwell Health, to advance human clinical trials and expand patient access to psychedelic therapy in Europe.

Posted on

New psychedelics??

Blue Sun Mycology Group Announces Filing of 2 US Patents for Methods Related to Inventing Impossible Novel Species of Psychoactive Fungi

If you think you’ve tried every psychedelic, think again 😉

An Oregon-based company called Blue Sun Mycology Group is preparing to file a patent for a process that combines foreign substances into fungi to create brand new drugs.

The company is just weeks away from harvesting the first batch of THC-infused psilocybin mushrooms and has started infusing LSD and DMT into mushrooms too!

Blue Sun Mycology recently filed 2 other patents for its process of creating new species of psychoactive fungi and plants through sexual hybridization, which it has already used to create over a dozen new species.

Posted on

The cure for writer’s block?

Kacey Musgraves on writing new album Star-crossed: “You aren’t owed a visit by the muse. She can visit or not visit”

Was Kacey Musgraves’ new album inspired by shrooms?

Two days before recording Star-crossed, Kacey went on a guided psilocybin journey that brought up a lot of feelings. She laid blindfolded and listened the Johns Hopkins psychedelic therapy playlist, which is curated by neuroscientists to trigger different emotions.

“Music has never sounded so good than it did when I was in that state,” she says. “You notice every nuance of every note. You react viscerally to it. And that served as a lot of the inspiration for the new record.”

She said that psilocybin helps people confront their demons, which “instantly makes them smaller”. After struggling through a recent divorce, the experience helped Musgraves find hope and gratitude for her other relationships in life.

Posted on

Microdosing: the solution all your problems

Meet the women who regularly microdose psychedelics

Three women struggling with mental health issues shared their life-changing experiences with microdosing.

One woman, Amber, was so depressed that everything felt dull and uninteresting, until she started microdosing. “When I microdosed for the first time I found myself noticing the beauty of the things around me again,” she says. She explains that microdosing is “akin to a child-like wonder” and makes her feel “more positive, open-minded and creative but still completely functional and sober”.

Bea finds that microdosing three times per week acts as a natural mood booster and study aid, brings her mental clarity, and helps her organize her life. She says she’s now able to be her true, stable self and is no longer the “people-pleasing, anxious version” of herself.

Chelsea says that microdosing allows her to “stay fully present” and is the only tool that helps her focus her busy mind, but the biggest shift was in her anxiety. “For over fifteen years, I had severe anxiety, but through microdosing, I could sit with and deliberate my fears. I now rarely suffer with it, and if I do, it’s fleeting,” she shares.

PDF of article

Posted on

The trendy parenting hack

Moms who microdose ‘magic’ mushrooms say the psychedelic made them better parents

 

Moms around the world are microdosing magic mushrooms to become better parents.

Natalie from Oakland, CA is one of many moms who’ve turned to microdoing to cope with postpartum depression. She was suffering so much that she was worried she’d harm her newborn, which made her suicidal.

Since microdosing 100mg of mushrooms daily for one month, she’s been able to go off antidepressants and ADHD medications. She says she feels more stable than ever and can now face motherhood with a sense of calm.

“Microdosing let me know who I really am…I’m able to parent myself and my daughter in a whole different way, because when I microdose, I know I’ve got this”, Natalie said in an interview with Insider.

Posted on

How to bond with strangers

Minnesota Psychedelic Therapy Clinic, Institute for Integrative Therapies, Begins Offering Psychedelic Therapy in a Group Setting

“We have a crisis of loneliness and isolation.” Is group psychedelic therapy the solution?

This week, the Institute for Integrative Therapies (IIT) in Minnesota began offering ketamine-assisted therapy in group settings, and will soon offer group therapy with psilocybin and MDMA too.

Group sessions can provide a powerful healing experience and a sense of connection, plus they’re much cheaper than one-on-one sessions at just $500 per person for a 3-hour experience.

Participants work with a therapist both individually and in group settings to prepare for the experience before laying on a floor mat and tripping in a room full of strangers. Each group has a focus such as depression, anxiety, PTSD, existential crises, grief, end of life distress, and LGBTQ experiences.

PDF of article

Posted on

Shrooms for dogs?

And you thought cannabis was crazy? Get ready for what’s next!

It may sound far-fetched, but psilocybin medicine could have therapeutic benefits for dogs!

As cannabis products are becoming more popular for pets, some progressive veterinarians are starting to explore the potential of magic mushrooms. Anecdotal evidence suggests that psilocybin may be able to help dogs with extreme anxiety, PTSD, or behavioural issues.* In parts of South America, psilocybin is used to enhance the hunting ability of dogs, and scientists hypothesize that substance can enhance a dog’s sense of smell and reduce extraneous signals.

*The Daily Mushroom does not encourage or condone giving psilocybin to dogs, as there is no published data on its effects.

PDF of article

Posted on

Psychedelics make you more open minded… obviously

Do our brains predict how we think? Psychedelics may help answer that question

It’s actually backed by science!

Research suggests that 5-HT2A serotonin receptors play an important role in a flexible thinking since they’re found in the region of the brain responsible for learning and cognition. A study conducted on rats found that when these receptors are blocked, the rats became unable to spontaneously change from one behaviour to another to earn a reward, indicating a decrease in cognitive flexibility.

Psilocybin activates the 5-HT2A serotonin receptors, as its chemical structure is quite similar to serotonin, which explains why so many users experience an increase in cognitive flexibility and a decrease in rigid thought patterns. Lack of cognitive flexibility is often associated with disorders like depression and OCD, so it makes sense that psilocybin is being used to treat these conditions!

PDF of article

Posted on

Psychedelic therapy from home

Wearable Psychedelics Could Soon Give Users Maximum Control Over Their Trip

Bexson Biomedical Inc. is developing a small wearable device that could allow users to control their psychedelic experiences from home.

The device attaches to the stomach and releases psychedelic compounds into a layer of fat via a tiny needle. In theory, users will be prescribed the pre-calibrated device and be able to use it in the comfort of their home. Users can preprogram the intensity and duration of the trip and potentially adjust the dose and rate of infusion throughout the trip.

This administration method would produce more consistent results across patients than oral administration, which can produce varying results due to differences in liver enzymes.

The device is currently being developed to administer ketamine for chronic pain, but could also be used for psilocybin, LSD, and DMT.

PDF of article